Other Species / Isoforms
  GAB2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsGGGDVVC
0 2
GAB2 (human) ______MsGGGDVVC S2-p
GAB2 iso2 (human) gap -
GAB2 (mouse) ______MSGGGGDDV S2
GAB2 (rat) ______MSGGGGDDV S2
Y48-p
GDPDVLEyyKNDHSK
0 29
GAB2 (human) GDPDVLEyyKNDHSK Y48-p
GAB2 iso2 (human) GDPDVLEYYKNDHSK Y10
GAB2 (mouse) GDPDVLEYYKNEHSK Y50
GAB2 (rat) GDPDVLEYYKNEHSK Y50
Y49-p
DPDVLEyyKNDHSKk
0 8
GAB2 (human) DPDVLEyyKNDHSKk Y49-p
GAB2 iso2 (human) DPDVLEYYKNDHSKK Y11
GAB2 (mouse) DPDVLEYYKNEHSKK Y51
GAB2 (rat) DPDVLEYYKNEHSKK Y51
K56-ac
yKNDHSKkPLRIINL
0 1
GAB2 (human) yKNDHSKkPLRIINL K56-ac
GAB2 iso2 (human) YKNDHSKKPLRIINL K18
GAB2 (mouse) YKNEHSKKPLRIINL K58
GAB2 (rat) YKNEHSKKPLRIINL K58
S133-p
DSLRNVSsAGHGPRs
Upstream
0 2
Treatment
  • EGF
GAB2 (human) DSLRNVSsAGHGPRs S133-p
GAB2 iso2 (human) DSLRNVSSAGHGPRS S95
GAB2 (mouse) DSLRNLSSASHGPRs S135
GAB2 (rat) DSLRNLSSASHGPRs S135
S140-p
sAGHGPRssPAELSS
Upstream
0 11
Treatment
  • EGF
GAB2 (human) sAGHGPRssPAELSS S140-p
GAB2 iso2 (human) SAGHGPRSSPAELSS S102
GAB2 (mouse) SASHGPRssPAEFsS S142-p
GAB2 (rat) SASHGPRssPAEFSS S142-p
S141-p
AGHGPRssPAELSSs
Upstream
0 15
Treatment
  • EGF
  • metastatic potential
GAB2 (human) AGHGPRssPAELSSs S141-p
GAB2 iso2 (human) AGHGPRSSPAELSSS S103
GAB2 (mouse) ASHGPRssPAEFsSS S143-p
GAB2 (rat) ASHGPRssPAEFSSS S143-p
S147
ssPAELSSssQHLLR
0 1
GAB2 (human) ssPAELSSssQHLLR S147
GAB2 iso2 (human) SSPAELSSSSQHLLR S109
GAB2 (mouse) RssPAEFsSSQHLLR S148-p
GAB2 (rat) RssPAEFSSSQHLLR S148
S148-p
sPAELSSssQHLLRE
Upstream
0 4
Treatment
  • EGF
GAB2 (human) sPAELSSssQHLLRE S148-p
GAB2 iso2 (human) SPAELSSSSQHLLRE S110
GAB2 (mouse) ssPAEFsSSQHLLRE S149
GAB2 (rat) ssPAEFSSSQHLLRE S149
S149-p
PAELSSssQHLLRER
Upstream
0 2
Treatment
  • EGF
GAB2 (human) PAELSSssQHLLRER S149-p
GAB2 iso2 (human) PAELSSSSQHLLRER S111
GAB2 (mouse) sPAEFsSSQHLLRER S150
GAB2 (rat) sPAEFSSSQHLLRER S150
S159-p
LLRERKSsAPSHsSQ
Upstream
Downstream
3 1
GAB2 (human)
S159-p
GAB2 (mouse)
S160-p
GAB2 (rat)
S160-p
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, altered
Kinase, in vitro:
  • Akt1 (human)
Putative in vivo kinases:
  • Akt1 (human)
Treatment
  • EGF
  • heregulin
GAB2 (human) LLRERKSsAPSHsSQ S159-p
GAB2 iso2 (human) LLRERKSSAPSHSSQ S121
GAB2 (mouse) LLRERKSsAPSHSsQ S160-p
GAB2 (rat) LLRERKSSAPSHSSQ S160
S164-p
KSsAPSHsSQPTLFt
0 1
GAB2 (human) KSsAPSHsSQPTLFt S164-p
GAB2 iso2 (human) KSSAPSHSSQPTLFT S126
GAB2 (mouse) KSsAPSHSsQPtLFT S165
GAB2 (rat) KSSAPSHSSQPTLFT S165
S165
SsAPSHsSQPTLFtF
0 1
GAB2 (human) SsAPSHsSQPTLFtF S165
GAB2 iso2 (human) SSAPSHSSQPTLFTF S127
GAB2 (mouse) SsAPSHSsQPtLFTF S166-p
GAB2 (rat) SSAPSHSSQPTLFTF S166
T168
PSHsSQPTLFtFEPP
0 1
GAB2 (human) PSHsSQPTLFtFEPP T168
GAB2 iso2 (human) PSHSSQPTLFTFEPP T130
GAB2 (mouse) PSHSsQPtLFTFEPP T169-p
GAB2 (rat) PSHSSQPTLFTFEPP T169
T171-p
sSQPTLFtFEPPVsN
0 1
GAB2 (human) sSQPTLFtFEPPVsN T171-p
GAB2 iso2 (human) SSQPTLFTFEPPVSN T133
GAB2 (mouse) SsQPtLFTFEPPVSS T172
GAB2 (rat) SSQPTLFTFEPPMTS T172
S177-p
FtFEPPVsNHMQPTL
0 1
GAB2 (human) FtFEPPVsNHMQPTL S177-p
GAB2 iso2 (human) FTFEPPVSNHMQPTL S139
GAB2 (mouse) FTFEPPVSSHMQPTL S178
GAB2 (rat) FTFEPPMTSHMQPAL T178
Y194-p
SAPQEYLyLHQCISR
0 1
GAB2 (human) SAPQEYLyLHQCISR Y194-p
GAB2 iso2 (human) SAPQEYLYLHQCISR Y156
GAB2 (mouse) SAPQEYLYLHQCISR Y195
GAB2 (rat) SAPQEYLYLHQCISR Y195
S208-p
RRAENARsAsFsQGT
0 1
GAB2 (human) RRAENARsAsFsQGT S208-p
GAB2 iso2 (human) RRAENARSASFSQGT S170
GAB2 (mouse) RRTENARSAsFSQGT S209
GAB2 (rat) RRTENSRSASFSQGT S209
S210-p
AENARsAsFsQGTRA
Upstream
Downstream
3 26
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell growth, altered
Regulatory protein:
  • PIK3CA (human)
Treatment
  • Akt-I-1,2
  • EGF
  • Go_6850
  • Go_6976
  • H-89
  • insulin
  • KN-62
  • LY294002
  • mPKI
  • rapamycin
  • U0126
  • wortmannin
  • Y27632
GAB2 (human) AENARsAsFsQGTRA S210-p
GAB2 iso2 (human) AENARSASFSQGTRA S172
GAB2 (mouse) TENARSAsFSQGTRQ S211-p
GAB2 (rat) TENSRSASFSQGTRQ S211
S212-p
NARsAsFsQGTRAsF
0 1
GAB2 (human) NARsAsFsQGTRAsF S212-p
GAB2 iso2 (human) NARSASFSQGTRASF S174
GAB2 (mouse) NARSAsFSQGTRQKS S213
GAB2 (rat) NSRSASFSQGTRQKS S213
S218-p
FsQGTRAsFLMRsDT
0 2
GAB2 (human) FsQGTRAsFLMRsDT S218-p
GAB2 iso2 (human) FSQGTRASFLMRSDT S180
GAB2 (mouse) gap -
GAB2 (rat) gap -
S223-p
RAsFLMRsDTAVQKL
Upstream
0 6
Treatment
  • EGF
GAB2 (human) RAsFLMRsDTAVQKL S223-p
GAB2 iso2 (human) RASFLMRSDTAVQKL S185
GAB2 (mouse) SQGTRQKSDTAVQKL S220
GAB2 (rat) SQGTRQKSDTAVQKL S220
G233
AVQKLAQGNGHCVNG
0 1
GAB2 (human) AVQKLAQGNGHCVNG G233
GAB2 iso2 (human) AVQKLAQGNGHCVNG G195
GAB2 (mouse) AVQKLAQsNGHCING S230-p
GAB2 (rat) AVQKLAQSNGHCING S230
Y249-p
SGQVHGFysLPKPSR
0 74
GAB2 (human) SGQVHGFysLPKPSR Y249-p
GAB2 iso2 (human) SGQVHGFYSLPKPSR Y211
GAB2 (mouse) GGQVHGFySLPKPSR Y246-p
GAB2 (rat) SNQVHGFYSLPKPSR Y246
S250-p
GQVHGFysLPKPSRH
0 8
GAB2 (human) GQVHGFysLPKPSRH S250-p
GAB2 iso2 (human) GQVHGFYSLPKPSRH S212
GAB2 (mouse) GQVHGFySLPKPSRH S247
GAB2 (rat) NQVHGFYSLPKPSRH S247
S264-p
HNTEFRDstyDLPRS
Upstream
0 24
Treatment
  • EGF
GAB2 (human) HNTEFRDstyDLPRS S264-p
GAB2 iso2 (human) HNTEFRDSTYDLPRS S226
GAB2 (mouse) HNTEFKDstyDLPRS S261-p
GAB2 (rat) HNTEFKDsTyDLPRS S261-p
T265-p
NTEFRDstyDLPRSL
0 10
GAB2 (human) NTEFRDstyDLPRSL T265-p
GAB2 iso2 (human) NTEFRDSTYDLPRSL T227
GAB2 (mouse) NTEFKDstyDLPRSL T262-p
GAB2 (rat) NTEFKDsTyDLPRSL T262
Y266-p
TEFRDstyDLPRSLA
Upstream
Downstream
1 238
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • ZAP70 (human)
GAB2 (human) TEFRDstyDLPRSLA Y266-p
GAB2 iso2 (human) TEFRDSTYDLPRSLA Y228
GAB2 (mouse) TEFKDstyDLPRSLA Y263-p
GAB2 (rat) TEFKDsTyDLPRSLA Y263-p
T278-p
SLASHGHtKGsLTGs
0 1
GAB2 (human) SLASHGHtKGsLTGs T278-p
GAB2 iso2 (human) SLASHGHTKGSLTGS T240
GAB2 (mouse) SLASHGHTKSSLTGS T275
GAB2 (rat) SLASHGHTKSSLTGS T275
S281-p
SHGHtKGsLTGsEtD
Upstream
0 2
Treatment
  • EGF
GAB2 (human) SHGHtKGsLTGsEtD S281-p
GAB2 iso2 (human) SHGHTKGSLTGSETD S243
GAB2 (mouse) SHGHTKSSLTGSEtD S278
GAB2 (rat) SHGHTKSSLTGSETD S278
S285-p
tKGsLTGsEtDNEDV
Upstream
0 3
Treatment
  • IL-2
GAB2 (human) tKGsLTGsEtDNEDV S285-p
GAB2 iso2 (human) TKGSLTGSETDNEDV S247
GAB2 (mouse) TKSSLTGSEtDNEDV S282
GAB2 (rat) TKSSLTGSETDNEDV S282
T287-p
GsLTGsEtDNEDVyt
Upstream
0 6
Treatment
  • EGF
GAB2 (human) GsLTGsEtDNEDVyt T287-p
GAB2 iso2 (human) GSLTGSETDNEDVYT T249
GAB2 (mouse) SSLTGSEtDNEDVyT T284-p
GAB2 (rat) SSLTGSETDNEDVYT T284
Y293-p
EtDNEDVytFKTPSN
Upstream
Downstream
1 183
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • EGF
  • FGF2
  • IL-2
GAB2 (human) EtDNEDVytFKTPSN Y293-p
GAB2 iso2 (human) ETDNEDVYTFKTPSN Y255
GAB2 (mouse) EtDNEDVyTFKMPSN Y290-p
GAB2 (rat) ETDNEDVYTFKMPSN Y290
T294-p
tDNEDVytFKTPSNT
0 7
GAB2 (human) tDNEDVytFKTPSNT T294-p
GAB2 iso2 (human) TDNEDVYTFKTPSNT T256
GAB2 (mouse) tDNEDVyTFKMPSNT T291
GAB2 (rat) TDNEDVYTFKMPSNT T291
T319-p
DNMDVPAtPLsAyQI
0 5
GAB2 (human) DNMDVPAtPLsAyQI T319-p
GAB2 iso2 (human) DNMDVPATPLSAYQI T281
GAB2 (mouse) DNMDVPTtPLsAyQI T316-p
GAB2 (rat) DNMDVPTTPLSAYQI T316
S322-p
DVPAtPLsAyQIPRT
0 17
GAB2 (human) DVPAtPLsAyQIPRT S322-p
GAB2 iso2 (human) DVPATPLSAYQIPRT S284
GAB2 (mouse) DVPTtPLsAyQIPRT S319-p
GAB2 (rat) DVPTTPLSAYQIPRT S319
Y324-p
PAtPLsAyQIPRTFt
0 146
GAB2 (human) PAtPLsAyQIPRTFt Y324-p
GAB2 iso2 (human) PATPLSAYQIPRTFT Y286
GAB2 (mouse) PTtPLsAyQIPRTFT Y321-p
GAB2 (rat) PTTPLSAYQIPRTFT Y321
T331-p
yQIPRTFtLDKNHNA
Upstream
0 2
Treatment
  • EGF
GAB2 (human) yQIPRTFtLDKNHNA T331-p
GAB2 iso2 (human) YQIPRTFTLDKNHNA T293
GAB2 (mouse) yQIPRTFTLDKNHNA T328
GAB2 (rat) YQIPRTFTLDKNHNA T328
S368-p
AETPRWGsPQQRPPI
Upstream
0 9
Treatment
  • IL-2
GAB2 (human) AETPRWGsPQQRPPI S368-p
GAB2 iso2 (human) AETPRWGSPQQRPPI S330
GAB2 (mouse) AETSQWGSIQQRPPI S365
GAB2 (rat) AETPRWGsPQQKPPI S365-p
S381
PISENSRSVAAtIPR
0 1
GAB2 (human) PISENSRSVAAtIPR S381
GAB2 iso2 (human) PISENSRSVAATIPR S343
GAB2 (mouse) PISENSRsVAATIPR S378-p
GAB2 (rat) PIGENSRSVAATIPR S378
T385-p
NSRSVAAtIPRRNtL
0 3
GAB2 (human) NSRSVAAtIPRRNtL T385-p
GAB2 iso2 (human) NSRSVAATIPRRNTL T347
GAB2 (mouse) NSRsVAATIPRRNtL T382
GAB2 (rat) NSRSVAATIPRRNTL T382
T391-p
AtIPRRNtLPAMDNS
Upstream
Downstream
2 73
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell growth, altered
Regulatory protein:
  • PIK3CA (human)
Treatment
  • Akt-I-1,2
  • EGF
  • Go_6850
  • Go_6976
  • H-89
  • IL-2
  • insulin
  • KN-62
  • LY294002
  • mPKI
  • rapamycin
  • U0126
  • wortmannin
  • Y27632
GAB2 (human) AtIPRRNtLPAMDNS T391-p
GAB2 iso2 (human) ATIPRRNTLPAMDNS T353
GAB2 (mouse) ATIPRRNtLPAMDNS T388-p
GAB2 (rat) ATIPRRNTLPAMDNS T388
S404-p
NSRLHRAssCEtyEy
0 18
GAB2 (human) NSRLHRAssCEtyEy S404-p
GAB2 iso2 (human) NSRLHRASSCETYEY S366
GAB2 (mouse) NSRLHRAssCEtyEY S401-p
GAB2 (rat) NSRLHRAsSCETYEY S401-p
S405-p
SRLHRAssCEtyEyP
0 27
GAB2 (human) SRLHRAssCEtyEyP S405-p
GAB2 iso2 (human) SRLHRASSCETYEYP S367
GAB2 (mouse) SRLHRAssCEtyEYP S402-p
GAB2 (rat) SRLHRAsSCETYEYP S402
T408-p
HRAssCEtyEyPQRG
0 3
GAB2 (human) HRAssCEtyEyPQRG T408-p
GAB2 iso2 (human) HRASSCETYEYPQRG T370
GAB2 (mouse) HRAssCEtyEYPARG T405-p
GAB2 (rat) HRAsSCETYEYPTRG T405
Y409-p
RAssCEtyEyPQRGG
Upstream
0 261
Treatment
  • FGF2
GAB2 (human) RAssCEtyEyPQRGG Y409-p
GAB2 iso2 (human) RASSCETYEYPQRGG Y371
GAB2 (mouse) RAssCEtyEYPARGS Y406-p
GAB2 (rat) RAsSCETYEYPTRGS Y406
Y411-p
ssCEtyEyPQRGGES
0 3
GAB2 (human) ssCEtyEyPQRGGES Y411-p
GAB2 iso2 (human) SSCETYEYPQRGGES Y373
GAB2 (mouse) ssCEtyEYPARGSGE Y408
GAB2 (rat) sSCETYEYPTRGSGE Y408
S422-p
GGESAGRsAEsMsDG
0 3
GAB2 (human) GGESAGRsAEsMsDG S422-p
GAB2 iso2 (human) GGESAGRSAESMSDG S384
GAB2 (mouse) SGESASWSAEPPGKT S420
GAB2 (rat) SGESASWSAESPGKT S420
S425-p
SAGRsAEsMsDGVGS
0 1
GAB2 (human) SAGRsAEsMsDGVGS S425-p
GAB2 iso2 (human) SAGRSAESMSDGVGS S387
GAB2 (mouse) SASWSAEPPGKTAVG P423
GAB2 (rat) SASWSAESPGKTAVG S423
S427-p
GRsAEsMsDGVGSFL
0 1
GAB2 (human) GRsAEsMsDGVGSFL S427-p
GAB2 iso2 (human) GRSAESMSDGVGSFL S389
GAB2 (mouse) gap -
GAB2 (rat) gap -
S448-p
GRSDSTNsEDNyVPM
0 2
GAB2 (human) GRSDSTNsEDNyVPM S448-p
GAB2 iso2 (human) GRSDSTNSEDNYVPM S410
GAB2 (mouse) GRSNSASSDDNyVPM S437
GAB2 (rat) GRSDSASSDENYVPM S437
Y452-p
STNsEDNyVPMNPGs
Downstream
6 32
GAB2 (human)
Y452-p
GAB2 (mouse)
Y441-p
GAB2 (rat)
Y441-p
Effects on Modified Protein
  • molecular association, regulation
GAB2 (human) STNsEDNyVPMNPGs Y452-p
GAB2 iso2 (human) STNSEDNYVPMNPGS Y414
GAB2 (mouse) SASSDDNyVPMNPGS Y441-p
GAB2 (rat) SASSDENYVPMNPGS Y441
S459-p
yVPMNPGsSTLLAME
0 2
GAB2 (human) yVPMNPGsSTLLAME S459-p
GAB2 iso2 (human) YVPMNPGSSTLLAME S421
GAB2 (mouse) yVPMNPGSSTLLAME S448
GAB2 (rat) YVPMNPGSSTLLAME S448
S472-p
MERAGDNsQsVyIPM
0 30
GAB2 (human) MERAGDNsQsVyIPM S472-p
GAB2 iso2 (human) MERAGDNSQSVYIPM S434
GAB2 (mouse) MERPGDNSQSVYIPM S461
GAB2 (rat) MERAGDNSQSAYIPM S461
S474-p
RAGDNsQsVyIPMsP
0 20
GAB2 (human) RAGDNsQsVyIPMsP S474-p
GAB2 iso2 (human) RAGDNSQSVYIPMSP S436
GAB2 (mouse) RPGDNSQSVYIPMsP S463
GAB2 (rat) RAGDNSQSAYIPMGP S463
Y476-p
GDNsQsVyIPMsPGA
Upstream
Downstream
1 196
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • EPOR (human)
Treatment
  • Epo
GAB2 (human) GDNsQsVyIPMsPGA Y476-p
GAB2 iso2 (human) GDNSQSVYIPMSPGA Y438
GAB2 (mouse) GDNSQSVYIPMsPGP Y465
GAB2 (rat) GDNSQSAYIPMGPGP Y465
S480-p
QsVyIPMsPGAHHFD
1 7
GAB2 (human) QsVyIPMsPGAHHFD S480-p
GAB2 iso2 (human) QSVYIPMSPGAHHFD S442
GAB2 (mouse) QSVYIPMsPGPHHFD S469-p
GAB2 (rat) QSAYIPMGPGPHHFD G469
S488-p
PGAHHFDsLGyPSTT
0 5
GAB2 (human) PGAHHFDsLGyPSTT S488-p
GAB2 iso2 (human) PGAHHFDSLGYPSTT S450
GAB2 (mouse) PGPHHFDPLGYPSTA P477
GAB2 (rat) PGPHHFDPLGYPSTA P477
Y491-p
HHFDsLGyPSTTLPV
0 5
GAB2 (human) HHFDsLGyPSTTLPV Y491-p
GAB2 iso2 (human) HHFDSLGYPSTTLPV Y453
GAB2 (mouse) HHFDPLGYPSTALPI Y480
GAB2 (rat) HHFDPLGYPSTALPI Y480
K542-m1
VIDELPFksPItKSW
0 1
GAB2 (human) VIDELPFksPItKSW K542-m1
GAB2 iso2 (human) VIDELPFKSPITKSW K504
GAB2 (mouse) VIDELPFKsPVTKsW K531
GAB2 (rat) VIDELPFKSPVTKSW K531
S543-p
IDELPFksPItKSWs
Upstream
0 49
Treatment
  • angiotensin_2
  • EGF
  • IL-2
  • ischemia
  • selumetinib
  • SII_angiotensin_2
  • vemurafenib
GAB2 (human) IDELPFksPItKSWs S543-p
GAB2 iso2 (human) IDELPFKSPITKSWS S505
GAB2 (mouse) IDELPFKsPVTKsWs S532-p
GAB2 (rat) IDELPFKSPVTKSWS S532
T546-p
LPFksPItKSWsRAN
Upstream
0 2
Treatment
  • Y27632
GAB2 (human) LPFksPItKSWsRAN T546-p
GAB2 iso2 (human) LPFKSPITKSWSRAN T508
GAB2 (mouse) LPFKsPVTKsWsRIN T535
GAB2 (rat) LPFKSPVTKSWSRIN T535
S548
FksPItKSWsRANHT
0 1
GAB2 (human) FksPItKSWsRANHT S548
GAB2 iso2 (human) FKSPITKSWSRANHT S510
GAB2 (mouse) FKsPVTKsWsRINHT S537-p
GAB2 (rat) FKSPVTKSWSRINHT S537
S550-p
sPItKSWsRANHTFN
0 2
GAB2 (human) sPItKSWsRANHTFN S550-p
GAB2 iso2 (human) SPITKSWSRANHTFN S512
GAB2 (mouse) sPVTKsWsRINHTFN S539-p
GAB2 (rat) SPVTKSWSRINHTFN S539
Y563-p
FNSSSSQyCRPISTQ
0 47
GAB2 (human) FNSSSSQyCRPISTQ Y563-p
GAB2 iso2 (human) FNSSSSQYCRPISTQ Y525
GAB2 (mouse) FNSSSSQYCRPISTQ Y552
GAB2 (rat) FNSSSSQYCRPISTQ Y552
Y584-p
SGDSEENyVPMQNPV
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
GAB2 (human) SGDSEENyVPMQNPV Y584-p
GAB2 iso2 (human) SGDSEENYVPMQNPV Y546
GAB2 (mouse) SGDSEENYVPMQNPV Y573
GAB2 (rat) SGDSEENYVPMQNPV Y573
S602
PVPSGTNSPAPKKST
1 0
GAB2 (human) PVPSGTNSPAPKKST S602
GAB2 iso2 (human) PVPSGTNSPAPKKST S564
GAB2 (mouse) PVPSGTNsPAPKKST S591-p
GAB2 (rat) PVPSGTNSPAPRKST S591
S611-p
APKKSTGsVDyLALD
0 3
GAB2 (human) APKKSTGsVDyLALD S611-p
GAB2 iso2 (human) APKKSTGSVDYLALD S573
GAB2 (mouse) APKKSTGsVDyLALD S600-p
GAB2 (rat) APRKSTGSVDYLALD S600
Y614-p
KSTGsVDyLALDFQP
Upstream
Downstream
6 62
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, altered
Putative in vivo kinases:
  • ZAP70 (human)
Regulatory protein:
  • EPOR (human)
Treatment
  • Epo
  • IL-2
GAB2 (human) KSTGsVDyLALDFQP Y614-p
GAB2 iso2 (human) KSTGSVDYLALDFQP Y576
GAB2 (mouse) KSTGsVDyLALDFQP Y603-p
GAB2 (rat) KSTGSVDYLALDFQP Y603
S622-p
LALDFQPssPsPHRK
Upstream
0 8
Treatment
  • EGF
GAB2 (human) LALDFQPssPsPHRK S622-p
GAB2 iso2 (human) LALDFQPSSPSPHRK S584
GAB2 (mouse) LALDFQPGsPsPHRK G611
GAB2 (rat) LALDFQPGSPSPHRK G611
S623-p
ALDFQPssPsPHRKP
Upstream
Downstream
2 20
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • ERK1 (human)
Treatment
  • EGF
GAB2 (human) ALDFQPssPsPHRKP S623-p
GAB2 iso2 (human) ALDFQPSSPSPHRKP S585
GAB2 (mouse) ALDFQPGsPsPHRKP S612-p
GAB2 (rat) ALDFQPGSPSPHRKP S612
S625-p
DFQPssPsPHRKPst
1 6
GAB2 (human) DFQPssPsPHRKPst S625-p
GAB2 iso2 (human) DFQPSSPSPHRKPST S587
GAB2 (mouse) DFQPGsPsPHRKPst S614-p
GAB2 (rat) DFQPGSPSPHRKPST S614
S631-p
PsPHRKPstsSVtsD
1 3
GAB2 (human) PsPHRKPstsSVtsD S631-p
GAB2 iso2 (human) PSPHRKPSTSSVTSD S593
GAB2 (mouse) PsPHRKPstSsVtsD S620-p
GAB2 (rat) PSPHRKPSTSSVTSD S620
T632-p
sPHRKPstsSVtsDE
0 2
GAB2 (human) sPHRKPstsSVtsDE T632-p
GAB2 iso2 (human) SPHRKPSTSSVTSDE T594
GAB2 (mouse) sPHRKPstSsVtsDE T621-p
GAB2 (rat) SPHRKPSTSSVTSDE T621
S633-p
PHRKPstsSVtsDEK
0 1
GAB2 (human) PHRKPstsSVtsDEK S633-p
GAB2 iso2 (human) PHRKPSTSSVTSDEK S595
GAB2 (mouse) PHRKPstSsVtsDEK S622
GAB2 (rat) PHRKPSTSSVTSDEK S622
S634
HRKPstsSVtsDEKV
0 2
GAB2 (human) HRKPstsSVtsDEKV S634
GAB2 iso2 (human) HRKPSTSSVTSDEKV S596
GAB2 (mouse) HRKPstSsVtsDEKV S623-p
GAB2 (rat) HRKPSTSSVTSDEKV S623
T636-p
KPstsSVtsDEKVDy
0 2
GAB2 (human) KPstsSVtsDEKVDy T636-p
GAB2 iso2 (human) KPSTSSVTSDEKVDY T598
GAB2 (mouse) KPstSsVtsDEKVDy T625-p
GAB2 (rat) KPSTSSVTSDEKVDY T625
S637-p
PstsSVtsDEKVDyV
0 5
GAB2 (human) PstsSVtsDEKVDyV S637-p
GAB2 iso2 (human) PSTSSVTSDEKVDYV S599
GAB2 (mouse) PstSsVtsDEKVDyV S626-p
GAB2 (rat) PSTSSVTSDEKVDYV S626
Y643-p
tsDEKVDyVQVDKEK
Upstream
Downstream
4 199
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, altered
Kinase, in vitro:
  • JAK2 (human)
Putative in vivo kinases:
  • JAK2 (human)
Regulatory protein:
  • EPOR (human)
Treatment
  • AG490
  • dasatinib
  • Epo
  • G-CSF
  • IL-2
GAB2 (human) tsDEKVDyVQVDKEK Y643-p
GAB2 iso2 (human) TSDEKVDYVQVDKEK Y605
GAB2 (mouse) tsDEKVDyVQVDKEK Y632-p
GAB2 (rat) TSDEKVDYVQVDKEK Y632
T651-p
VQVDKEKtQALQNtM
0 1
GAB2 (human) VQVDKEKtQALQNtM T651-p
GAB2 iso2 (human) VQVDKEKTQALQNTM T613
GAB2 (mouse) VQVDKEKTQALQNTM T640
GAB2 (rat) VQVDKEKTQALQNTM T640
T657-p
KtQALQNtMQEWTDV
0 1
GAB2 (human) KtQALQNtMQEWTDV T657-p
GAB2 iso2 (human) KTQALQNTMQEWTDV T619
GAB2 (mouse) KTQALQNTMQEWTDV T646
GAB2 (rat) KTQALQNTMQEWTDV T646