Other Species / Isoforms
  USP8 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S6-p
__MPAVAsVPKELYL
0 1
USP8 (human) __MPAVAsVPKELYL S6-p
USP8 (mouse) __MPAVASVPKELYL S6
USP8 (rat) __MPAVASVPKELYL S6
R51-m1
FKTAEECrLDrDEER
0 1
USP8 (human) FKTAEECrLDrDEER R51-m1
USP8 (mouse) FKTAEECRLDRDEER R51
USP8 (rat) FKAAEECRLDRDEER R51
R54-m1
AEECrLDrDEERAYV
0 1
USP8 (human) AEECrLDrDEERAYV R54-m1
USP8 (mouse) AEECRLDRDEERAYV R54
USP8 (rat) AEECRLDRDEERAYV R54
S108-p
EAERLSEsLKLRyEE
0 2
USP8 (human) EAERLSEsLKLRyEE S108-p
USP8 (mouse) EAERLSEsLKLRYEE S108-p
USP8 (rat) EAERLSESLKLRYEE S108
Y113-p
SEsLKLRyEEAEVRK
0 1
USP8 (human) SEsLKLRyEEAEVRK Y113-p
USP8 (mouse) SEsLKLRYEEAEVRK Y113
USP8 (rat) SESLKLRYEEAEVRK Y113
S153-p
GGTLAKGsLENVLDs
0 12
USP8 (human) GGTLAKGsLENVLDs S153-p
USP8 (mouse) SGAAAKRsVENLLDs S153-p
USP8 (rat) SGAAAKRsVENLLDS S153-p
S160-p
sLENVLDsKDKTQKS
Upstream
0 5
Treatment
  • nocodazole
USP8 (human) sLENVLDsKDKTQKS S160-p
USP8 (mouse) sVENLLDsKtKtQRI S160-p
USP8 (rat) sVENLLDSKTKIQRV S160
D162
ENVLDsKDKTQKSNG
0 1
USP8 (human) ENVLDsKDKTQKSNG D162
USP8 (mouse) ENLLDsKtKtQRING T162-p
USP8 (rat) ENLLDSKTKIQRVNG T162
T164
VLDsKDKTQKSNGEK
0 1
USP8 (human) VLDsKDKTQKSNGEK T164
USP8 (mouse) LLDsKtKtQRINGEK T164-p
USP8 (rat) LLDSKTKIQRVNGEK I164
T351-p
PSKPAAQtPPASIEV
0 1
USP8 (human) PSKPAAQtPPASIEV T351-p
USP8 (mouse) PSKLPTQMPPPPIET M351
USP8 (rat) PSKLPAQMPPPPLEA M351
S378-p
RMGPLNIstPVEPVA
0 2
USP8 (human) RMGPLNIstPVEPVA S378-p
USP8 (mouse) QDEKLRLSTQPALAG S375
USP8 (rat) gap -
T379-p
MGPLNIstPVEPVAA
Upstream
0 17
Treatment
  • ischemia
USP8 (human) MGPLNIstPVEPVAA T379-p
USP8 (mouse) DEKLRLSTQPALAGP T376
USP8 (rat) DGKPRPLVQSALAGP V376
S389-p
EPVAASKsDVsPIIQ
0 7
USP8 (human) EPVAASKsDVsPIIQ S389-p
USP8 (mouse) GPGAAPRAEAsPIIQ A389
USP8 (rat) GPSVAPKAEASPIIQ A389
S392-p
AASKsDVsPIIQPVP
Upstream
0 16
Treatment
  • nocodazole
USP8 (human) AASKsDVsPIIQPVP S392-p
USP8 (mouse) AAPRAEAsPIIQPAP S392-p
USP8 (rat) VAPKAEASPIIQPVP S392
S400-p
PIIQPVPsIKNVPQI
0 6
USP8 (human) PIIQPVPsIKNVPQI S400-p
USP8 (mouse) PIIQPAPATKSVPQV A400
USP8 (rat) PIIQPVPATKNVPQV A400
T410-p
NVPQIDRtKKPAVKL
0 1
USP8 (human) NVPQIDRtKKPAVKL T410-p
USP8 (mouse) SVPQVDRTKKPSVKL T410
USP8 (rat) NVPQVDRTKKPAVKL T410
S434-p
STNHEQQsPQSGKVI
0 3
USP8 (human) STNHEQQsPQSGKVI S434-p
USP8 (mouse) gap -
USP8 (rat) gap -
T446
KVIPDRSTKPVVFsP
0 1
USP8 (human) KVIPDRSTKPVVFsP T446
USP8 (mouse) RVLSDRStKPVFPSP T440-p
USP8 (rat) RVLSDRSTKPVFTSP T440
S452-p
STKPVVFsPtLMLTD
Upstream
0 19
Treatment
  • ischemia
  • selumetinib
  • vemurafenib
view more >
USP8 (human) STKPVVFsPtLMLTD S452-p
USP8 (mouse) StKPVFPSPTTMLTD S446
USP8 (rat) STKPVFTSPATMLTD S446
T454-p
KPVVFsPtLMLTDEE
0 2
USP8 (human) KPVVFsPtLMLTDEE T454-p
USP8 (mouse) KPVFPSPTTMLTDEE T448
USP8 (rat) KPVFTSPATMLTDEE A448
K528
AKEEMEKKESEQAKK
0 1
USP8 (human) AKEEMEKKESEQAKK K528
USP8 (mouse) AKDGQEKkDSkQTkT K522-ac
USP8 (rat) AKDGQEKRDSKQTKA R522
E531
EMEKKESEQAKKEDk
0 1
USP8 (human) EMEKKESEQAKKEDk E531
USP8 (mouse) GQEKkDSkQTkTEDR K525-ac
USP8 (rat) GQEKRDSKQTKAEDR K525
K534
KKESEQAKKEDkETS
0 1
USP8 (human) KKESEQAKKEDkETS K534
USP8 (mouse) KkDSkQTkTEDRELS K528-ac
USP8 (rat) KRDSKQTKAEDREPP K528
K538-ac
EQAKKEDkETSAKRG
0 1
USP8 (human) EQAKKEDkETSAKRG K538-ac
USP8 (mouse) kQTkTEDRELSADGA R532
USP8 (rat) KQTKAEDREPPADGA R532
K566-ub
HETSDAKkSVEDRGK
0 1
USP8 (human) HETSDAKkSVEDRGK K566-ub
USP8 (mouse) HEASDAKVPVEGKRC V560
USP8 (rat) HDASDAKVSVEGKRC V560
T577-p
DRGKRCPtPEIQKKS
Upstream
0 40
Treatment
  • BI2536
USP8 (human) DRGKRCPtPEIQKKS T577-p
USP8 (mouse) VEGKRCPTSEAQKRP T569
USP8 (rat) VEGKRCPMSEVQKRP M569
S597-p
HTSVTGDsGsGkPFK
0 1
USP8 (human) HTSVTGDsGsGkPFK S597-p
USP8 (mouse) PASVSGELNAGKAQR L588
USP8 (rat) ASSMSGELSAGKAQR L589
S599-p
SVTGDsGsGkPFKIK
0 1
USP8 (human) SVTGDsGsGkPFKIK S599-p
USP8 (mouse) SVSGELNAGKAQREP A590
USP8 (rat) SMSGELSAGKAQREP A591
K601-ac
TGDsGsGkPFKIKGQ
0 1
USP8 (human) TGDsGsGkPFKIKGQ K601-ac
USP8 (mouse) SGELNAGKAQREPLT K592
USP8 (rat) SGELSAGKAQREPLT K593
S611-p
KIKGQPEsGILRTGt
0 1
USP8 (human) KIKGQPEsGILRTGt S611-p
USP8 (mouse) gap -
USP8 (rat) gap -
T618-p
sGILRTGtFREDTDD
Upstream
0 9
Treatment
  • ischemia
USP8 (human) sGILRTGtFREDTDD T618-p
USP8 (mouse) gap -
USP8 (rat) gap -
S641-p
EPLTRARsEEMGRIV
0 25
USP8 (human) EPLTRARsEEMGRIV S641-p
USP8 (mouse) EPLTRARsEEMGRIV S603-p
USP8 (rat) EPLTRARSEEMGRIV S604
S653-p
RIVPGLPsGWAKFLD
0 1
USP8 (human) RIVPGLPsGWAKFLD S653-p
USP8 (mouse) RIVPGLPLGWAKFLD L615
USP8 (rat) RIVPGLPLGWAKFLD L616
Y668-p
PITGTFRyYHsPtNt
0 1
USP8 (human) PITGTFRyYHsPtNt Y668-p
USP8 (mouse) PITGTFRYYHSPTNT Y630
USP8 (rat) PITGTFRYYHSPTNT Y631
S671-p
GTFRyYHsPtNtVHM
0 4
USP8 (human) GTFRyYHsPtNtVHM S671-p
USP8 (mouse) GTFRYYHSPTNTVHM S633
USP8 (rat) GTFRYYHSPTNTVHM S634
T673-p
FRyYHsPtNtVHMYP
0 1
USP8 (human) FRyYHsPtNtVHMYP T673-p
USP8 (mouse) FRYYHSPTNTVHMYP T635
USP8 (rat) FRYYHSPTNTVHMYP T636
T675-p
yYHsPtNtVHMYPPE
0 1
USP8 (human) yYHsPtNtVHMYPPE T675-p
USP8 (mouse) YYHSPTNTVHMYPPE T637
USP8 (rat) YYHSPTNTVHMYPPE T638
S686-p
YPPEMAPssAPPstP
0 1
USP8 (human) YPPEMAPssAPPstP S686-p
USP8 (mouse) YPPEMAPSSAPPSTP S648
USP8 (rat) YPPEMAPSSVPPSTP S649
S687-p
PPEMAPssAPPstPP
0 1
USP8 (human) PPEMAPssAPPstPP S687-p
USP8 (mouse) PPEMAPSSAPPSTPP S649
USP8 (rat) PPEMAPSSVPPSTPP S650
S691-p
APssAPPstPPtHKA
0 11
USP8 (human) APssAPPstPPtHKA S691-p
USP8 (mouse) APSSAPPSTPPTHKV S653
USP8 (rat) APSSVPPSTPPTHKV S654
T692-p
PssAPPstPPtHKAK
0 16
USP8 (human) PssAPPstPPtHKAK T692-p
USP8 (mouse) PSSAPPSTPPTHKVK T654
USP8 (rat) PSSVPPSTPPTHKVK T655
T695-p
APPstPPtHKAKPQI
0 3
USP8 (human) APPstPPtHKAKPQI T695-p
USP8 (mouse) APPSTPPTHKVKPQV T657
USP8 (rat) VPPSTPPTHKVKPQI T658
S711-p
AERDREPsKLKRsys
Upstream
0 1
Treatment
  • BI2536
USP8 (human) AERDREPsKLKRsys S711-p
USP8 (mouse) AERDREPSKLKRsYs S673
USP8 (rat) AERDREPSKLKRsYs S674
S716-p
EPsKLKRsyssPDIt
Upstream
0 12
Treatment
  • Y27632
USP8 (human) EPsKLKRsyssPDIt S716-p
USP8 (mouse) EPSKLKRsYssPDIt S678-p
USP8 (rat) EPSKLKRsYsSPDIT S679-p
Y717-p
PsKLKRsyssPDItQ
Upstream
Downstream
1 5
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • EGFR (human)
USP8 (human) PsKLKRsyssPDItQ Y717-p
USP8 (mouse) PSKLKRsYssPDItQ Y679
USP8 (rat) PSKLKRsYsSPDITQ Y680
S718-p
sKLKRsyssPDItQA
Upstream
Downstream
4 96
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
Putative upstream phosphatases:
  • PPP1CA (human)
Treatment
  • EGF
  • LY294002
  • metastatic potential
  • nocodazole
  • okadaic_acid
view more >
USP8 (human) sKLKRsyssPDItQA S718-p
USP8 (mouse) SKLKRsYssPDItQA S680-p
USP8 (rat) SKLKRsYsSPDITQA S681-p
S719-p
KLKRsyssPDItQAI
Upstream
0 14
Treatment
  • metastatic potential
  • Y27632
USP8 (human) KLKRsyssPDItQAI S719-p
USP8 (mouse) KLKRsYssPDItQAL S681-p
USP8 (rat) KLKRsYsSPDITQAL S682
T723-p
syssPDItQAIQEEE
0 3
USP8 (human) syssPDItQAIQEEE T723-p
USP8 (mouse) sYssPDItQALQEEE T685-p
USP8 (rat) sYsSPDITQALQEEE T686
T737-p
EKRKPTVtPtVNREN
0 2
USP8 (human) EKRKPTVtPtVNREN T737-p
USP8 (mouse) EKRRPAVTPMVNREN T699
USP8 (rat) EKRRPAVTPTVNREN T700
T739-p
RKPTVtPtVNRENKP
0 1
USP8 (human) RKPTVtPtVNRENKP T739-p
USP8 (mouse) RRPAVTPMVNRENKP M701
USP8 (rat) RRPAVTPTVNRENKP T702
S760
EISRLSASQIRNLNP
0 1
USP8 (human) EISRLSASQIRNLNP S760
USP8 (mouse) EISRLSAsQIRNLNP S722-p
USP8 (rat) EISRLSASQIRNLNP S723
Y810-p
DYFNRNCyQDDINRS
Upstream
Downstream
1 2
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • EGFR (human)
USP8 (human) DYFNRNCyQDDINRS Y810-p
USP8 (mouse) DYFNRNCYQDDINRS Y772
USP8 (rat) DYFNRNCYQDDINRS Y773
Y842-p
KALWTGQyRYISPKD
0 3
USP8 (human) KALWTGQyRYISPKD Y842-p
USP8 (mouse) KALWTGQYRYISPKD Y804
USP8 (rat) KALWTGQYRYISPKD Y805
K905-ub
NDHLDDFkAAEHAWQ
0 1
USP8 (human) NDHLDDFkAAEHAWQ K905-ub
USP8 (mouse) NEHLDDLQAAEHAWQ Q867
USP8 (rat) NDHLDDFKAAEHAWQ K868
T945
TCHKKSRTFEAFMyL
1 0
USP8 (human) TCHKKSRTFEAFMyL T945
USP8 (mouse) TCRRRSRtFEAFMYL T907-p
USP8 (rat) TCHKKSRTFEAFMYL T908
Y951-p
RTFEAFMyLSLPLAS
0 1
USP8 (human) RTFEAFMyLSLPLAS Y951-p
USP8 (mouse) RtFEAFMYLSLPLAS Y913
USP8 (rat) RTFEAFMYLSLPLAS Y914
N980
KEEKLTDNNRFYCSH
0 1
USP8 (human) KEEKLTDNNRFYCSH N980
USP8 (mouse) KEEKLTDnnRFYCSH N942-ng
USP8 (rat) KEEKLTDNNRFYCSH N943
N981
EEKLTDNNRFYCSHC
0 1
USP8 (human) EEKLTDNNRFYCSHC N981
USP8 (mouse) EEKLTDnnRFYCSHC N943-ng
USP8 (rat) EEKLTDNNRFYCSHC N944
S1015-p
LVHLKRFsyDGRWKQ
0 2
USP8 (human) LVHLKRFsyDGRWKQ S1015-p
USP8 (mouse) LVHLKRFsYDGRWKQ S977-p
USP8 (rat) LVHLKRFSYDGRWKQ S978
Y1016-p
VHLKRFsyDGRWKQK
0 1
USP8 (human) VHLKRFsyDGRWKQK Y1016-p
USP8 (mouse) VHLKRFsYDGRWKQK Y978
USP8 (rat) VHLKRFSYDGRWKQK Y979
Y1068-p
GGLDGGHyTAYCKNA
0 1
USP8 (human) GGLDGGHyTAYCKNA Y1068-p
USP8 (mouse) GGLDGGHYTAYCKNA Y1030
USP8 (rat) GGLDGGHYTAYCKNA Y1031
Y1106-p
SAAYILFyTSLGPRV
0 1
USP8 (human) SAAYILFyTSLGPRV Y1106-p
USP8 (mouse) SAAYILFYTSLGPRI Y1068
USP8 (rat) SAAYILFYTSLGPRV Y1069