Other Species / Isoforms
  TH (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T3-p
_____MPtPDATTPQ
0 1
TH (human) _____MPtPDATTPQ T3-p
TH iso2 (human) _____MPTPDATTPQ T3
TH iso3 (human) _____MPTPDATTPQ T3
TH iso4 (human) _____MPTPDATTPQ T3
TH (mouse) _____MPTPSASSPQ T3
TH (rat) _____MPTPSAPsPQ T3
TH (cow) _____MPTPNAASPQ T3
T8
MPtPDATTPQAKGFR
5 1
TH (human) MPtPDATTPQAKGFR T8
TH iso2 (human) MPTPDATTPQAKGFR T8
TH iso3 (human) MPTPDATTPQAKGFR T8
TH iso4 (human) MPTPDATTPQAKGFR T8
TH (mouse) MPTPSASSPQPKGFR S8
TH (rat) MPTPSAPsPQPKGFR S8-p
TH (cow) MPTPNAASPQAKGFR S8
S19-p
KGFRRAVsELDAKQA
Upstream
Downstream
42 13
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • protein conformation
Kinase, in vitro:
  • CAMK2A (human)
  • CAMK2A (rat)
  • MAPKAPK2 (human)
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Phosphatases, in vitro:
  • PPP2CA (human)
Putative in vivo kinases:
  • CAMK2A (human)
Treatment
  • AIDA
  • CNQX
  • CPP
  • GDNF
  • LY341495
  • MCCG
  • MK801
  • MSOP
  • serum_starvation
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TH (human) KGFRRAVsELDAKQA S19-p
TH iso2 (human) KGFRRAVsELDAKQA S19-p
TH iso3 (human) KGFRRAVsELDAKQA S19-p
TH iso4 (human) KGFRRAVsELDAKQA S19-p
TH (mouse) KGFRRAVsEQDtKQA S19-p
TH (rat) KGFRRAVsEQDAKQA S19-p
TH (cow) KGFRRAVsELDAKQA S19-p
A23
RAVsELDAKQAEAIM
0 1
TH (human) RAVsELDAKQAEAIM A23
TH iso2 (human) RAVsELDAKQAEAIM A23
TH iso3 (human) RAVsELDAKQAEAIM A23
TH iso4 (human) RAVsELDAKQAEAIM A23
TH (mouse) RAVsEQDtKQAEAVt T23-p
TH (rat) RAVsEQDAKQAEAVT A23
TH (cow) RAVsELDAKQAEAIM A23
M30
AKQAEAIMVRGQGAP
0 1
TH (human) AKQAEAIMVRGQGAP M30
TH iso2 (human) AKQAEAIMGAPGPSL M30
TH iso3 (human) AKQAEAIMsPRFIGR M30
TH iso4 (human) AKQAEAIMVRGQsPR M30
TH (mouse) tKQAEAVtsPRFIGR T30-p
TH (rat) AKQAEAVTsPRFIGR T30
TH (cow) AKQAEAIMsPRFVGR M30
S62-p
SYTPTPRsPRFIGRR
Upstream
Downstream
38 7
TH (mouse)
S31-p
TH (rat)
S31-p
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
TH (human) SYTPTPRsPRFIGRR S62-p
TH iso2 (human) SYTPTPRsPRFIGRR S58-p
TH iso3 (human) KQAEAIMsPRFIGRR S31-p
TH iso4 (human) AIMVRGQsPRFIGRR S35-p
TH (mouse) KQAEAVtsPRFIGRR S31-p
TH (rat) KQAEAVTsPRFIGRR S31-p
TH (cow) KQAEAIMsPRFVGRR S31-p
S71-p
RFIGRRQsLIEDARK
Upstream
Downstream
56 16
TH (human)
S71-p
TH iso2 (human)
S67-p
TH iso3 (human)
S40-p
TH iso4 (human)
S44-p
TH (mouse)
S40-p
TH (rat)
S40-p
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • CAMK2A (human)
  • CAMK2A (rat)
  • MAPKAPK2 (human)
  • PKACA (cow)
  • PKACA (human)
  • RSK2 (human)
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Phosphatases, in vitro:
  • PPP2CA (human)
TH (human) RFIGRRQsLIEDARK S71-p
TH iso2 (human) RFIGRRQsLIEDARK S67-p
TH iso3 (human) RFIGRRQsLIEDARK S40-p
TH iso4 (human) RFIGRRQsLIEDARK S44-p
TH (mouse) RFIGRRQsLIEDARK S40-p
TH (rat) RFIGRRQsLIEDARK S40-p
TH (cow) RFVGRRQsLIQDARK S40-p
S118-p
AVLNLLFsPRATKPS
0 1
TH (human) AVLNLLFsPRATKPS S118-p
TH iso2 (human) AVLNLLFSPRATKPS S114
TH iso3 (human) AVLNLLFSPRATKPS S87
TH iso4 (human) AVLNLLFSPRATKPS S91
TH (mouse) AVLNLLFSLRGTKPS S88
TH (rat) AVLNLLFSLRGTKPS S88
TH (cow) AVLTLLFALPPTRPP A81
S183
LSGVRQVSEDVRSPA
1 0
TH (human) LSGVRQVSEDVRSPA S183
TH iso2 (human) LSGVRQVSEDVRSPA S179
TH iso3 (human) LSGVRQVSEDVRSPA S152
TH iso4 (human) LSGVRQVSEDVRSPA S156
TH (mouse) LSSVRRVSDDVRSAR S153
TH (rat) LSSVRRVsDDVRSAR S153-p
TH (cow) LSALRRVAEDVRAAG A146
Y230-p
PGFSDQVyRQRRKLI
0 1
TH (human) PGFSDQVyRQRRKLI Y230-p
TH iso2 (human) PGFSDQVYRQRRKLI Y226
TH iso3 (human) PGFSDQVYRQRRKLI Y199
TH iso4 (human) PGFSDQVYRQRRKLI Y203
TH (mouse) PGFSDQAYRQRRKLI Y200
TH (rat) PGFSDQVYRQRRKLI Y200
TH (cow) PGFSDQAYRQRRKLI Y193
Y419-p
QNGEVKAyGAGLLSS
0 1
TH (human) QNGEVKAyGAGLLSS Y419-p
TH iso2 (human) QNGEVKAYGAGLLSS Y415
TH iso3 (human) QNGEVKAYGAGLLSS Y388
TH iso4 (human) QNGEVKAYGAGLLSS Y392
TH (mouse) QNGELKAYGAGLLSS Y389
TH (rat) QNGELKAYGAGLLSS Y389
TH (cow) QNGEVKAYGAGLLSS Y382
S435
GELLHCLSEEPEIRA
1 0
TH (human) GELLHCLSEEPEIRA S435
TH iso2 (human) GELLHCLSEEPEIRA S431
TH iso3 (human) GELLHCLsEEPEIRA S404-p
TH iso4 (human) GELLHCLSEEPEIRA S408
TH (mouse) GELLHSLSEEPEVRA S405
TH (rat) GELLHSLSEEPEVRA S405
TH (cow) GELLHSLSEEPEIRA S398
S502-p
LAIDVLDsPQAVRRS
0 4
TH (human) LAIDVLDsPQAVRRS S502-p
TH iso2 (human) LAIDVLDSPQAVRRS S498
TH iso3 (human) LAIDVLDSPQAVRRS S471
TH iso4 (human) LAIDVLDSPQAVRRS S475
TH (mouse) LAIDVLDsPHTIRRS S472-p
TH (rat) LAIDVLDsPHTIQRS S472-p
TH (cow) LAIDVLDSPHAIRHA S465