Other Species / Isoforms
  TRF1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S7-p
_MAEDVSsAAPsPRG
0 5
TRF1 (human) _MAEDVSsAAPsPRG S7-p
TRF1 (mouse) _MAETVSSAARDAPS S7
TRF1 (rat) _MAGTVTSAAPGARS S7
S11-p
DVSsAAPsPRGCADG
Upstream
0 17
Regulatory protein:
  • PLK1 (human)
Treatment
  • nocodazole
  • ZK-Thiazolidinone
TRF1 (human) DVSsAAPsPRGCADG S11-p
TRF1 (mouse) gap -
TRF1 (rat) TVTSAAPGARSNAGG G11
R33
EQMAETERNDEEQFE
0 1
TRF1 (human) EQMAETERNDEEQFE R33
TRF1 (mouse) EGWTDSDSPEQEEVG S23
TRF1 (rat) AGGTSADsPEKEAAR S23-p
S114-p
AIIHGLSsLTACQLR
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
Kinase, in vitro:
  • NEK2 (human)
Putative in vivo kinases:
  • NEK7 (human)
Treatment
  • light
TRF1 (human) AIIHGLSsLTACQLR S114-p
TRF1 (mouse) AIIHGLHRLTAYQLK R101
TRF1 (rat) AIIHGLPSLTAYQLK S101
T122-p
LTACQLRtIYICQFL
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • DRB
  • siRNA
TRF1 (human) LTACQLRtIYICQFL T122-p
TRF1 (mouse) LTAYQLKTVYICQFL T109
TRF1 (rat) LTAYQLKTVYICQFL T109
K136-ub
LTRIAAGkTLDAQFE
0 3
TRF1 (human) LTRIAAGkTLDAQFE K136-ub
TRF1 (mouse) LTRVASGKALDAQFE K123
TRF1 (rat) LTRVAAGKSLDAQFE K123
T149-p
FENDERItPLESALM
0 1
TRF1 (human) FENDERItPLESALM T149-p
TRF1 (mouse) FEVDERITPLESALM T136
TRF1 (rat) FEVDERITPLESALM T136
S160-p
SALMIWGsIEKEHDk
0 1
TRF1 (human) SALMIWGsIEKEHDk S160-p
TRF1 (mouse) SALMIWNSIEKEHDK S147
TRF1 (rat) SALMIWDSIEKEHDK S147
K167-ub
sIEKEHDkLHEEIQN
0 1
TRF1 (human) sIEKEHDkLHEEIQN K167-ub
TRF1 (mouse) SIEKEHDKLHDEIKN K154
TRF1 (rat) SIEKEHDKLHEEIQN K154
S219-p
SKLLMIIsQKDTFHS
Upstream
Downstream
1 0
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
  • neocarzinostatin
  • wortmannin
TRF1 (human) SKLLMIIsQKDTFHS S219-p
TRF1 (mouse) RKLLKIISQKDVFHS S206
TRF1 (rat) RKLLKIISQKDVFHV S206
K241-ac
NHMMEKIkSYVNYVL
0 1
TRF1 (human) NHMMEKIkSYVNYVL K241-ac
TRF1 (mouse) SCMMEKIQSYVGDVL Q228
TRF1 (rat) NLMMEKIQSYVECVL Q228
S252-p
NYVLSEKsstFLMKA
0 1
TRF1 (human) NYVLSEKsstFLMKA S252-p
TRF1 (mouse) GDVLSEKSSTFLMKA S239
TRF1 (rat) ECVLNEKSSTFLMKA S239
S253-p
YVLSEKsstFLMKAA
0 1
TRF1 (human) YVLSEKsstFLMKAA S253-p
TRF1 (mouse) DVLSEKSSTFLMKAA S240
TRF1 (rat) CVLNEKSSTFLMKAA S240
T254-p
VLSEKsstFLMKAAA
0 1
TRF1 (human) VLSEKsstFLMKAAA T254-p
TRF1 (mouse) VLSEKSSTFLMKAAT T241
TRF1 (rat) VLNEKSSTFLMKAAT T241
T271-p
VESKRTRtItSQDKP
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell cycle regulation
TRF1 (human) VESKRTRtItSQDKP T271-p
TRF1 (mouse) VENEKARTQAsKDRP T258
TRF1 (rat) VENEKARTVASEDKA T258
T273-p
SKRTRtItSQDKPSG
Upstream
1 0
Kinase, in vitro:
  • Akt1 (human)
TRF1 (human) SKRTRtItSQDKPSG T273-p
TRF1 (mouse) NEKARTQAsKDRPDA A260
TRF1 (rat) NEKARTVASEDKAKA A260
S274
KRTRtItSQDKPSGN
0 1
TRF1 (human) KRTRtItSQDKPSGN S274
TRF1 (mouse) EKARTQAsKDRPDAt S261-p
TRF1 (rat) EKARTVASEDKAKAT S261
N281
SQDKPSGNDVEMETE
0 1
TRF1 (human) SQDKPSGNDVEMETE N281
TRF1 (mouse) sKDRPDAtNtGMDTE T268-p
TRF1 (rat) SEDKAKATNTGTETE T268
V283
DKPSGNDVEMETEAN
0 1
TRF1 (human) DKPSGNDVEMETEAN V283
TRF1 (mouse) DRPDAtNtGMDTEVG T270-p
TRF1 (rat) DKAKATNTGTETEVN T270
K295-ac
EANLDTRksVSDkQS
0 1
TRF1 (human) EANLDTRksVSDkQS K295-ac
TRF1 (mouse) EVGLNKEKSVNGQQS K282
TRF1 (rat) EVNSNKGESVNGQQS E282
S296-p
ANLDTRksVSDkQSA
0 2
TRF1 (human) ANLDTRksVSDkQSA S296-p
TRF1 (mouse) VGLNKEKSVNGQQST S283
TRF1 (rat) VNSNKGESVNGQQSV S283
K300-ac
TRksVSDkQSAVTES
0 1
TRF1 (human) TRksVSDkQSAVTES K300-ac
TRF1 (mouse) KEKSVNGQQSTETEP Q287
TRF1 (rat) KGESVNGQQSVETES Q287
K300-ub
TRksVSDkQSAVTES
0 1
TRF1 (human) TRksVSDkQSAVTES K300-ub
TRF1 (mouse) under review -
TRF1 (rat) under review -
S308-p
QSAVTESsEGtVSLL
0 1
TRF1 (human) QSAVTESsEGtVSLL S308-p
TRF1 (mouse) QSTETEPLVDTVSSI L295
TRF1 (rat) QSVETESLVDTGSSV L295
T311-p
VTESsEGtVSLLRSH
0 1
TRF1 (human) VTESsEGtVSLLRSH T311-p
TRF1 (mouse) ETEPLVDTVSSIRSH T298
TRF1 (rat) ETESLVDTGSSVRSH T298
K319-ub
VSLLRSHkNLFLSkL
0 1
TRF1 (human) VSLLRSHkNLFLSkL K319-ub
TRF1 (mouse) under review -
TRF1 (rat) under review -
S324
SHkNLFLSkLQHGtQ
0 1
TRF1 (human) SHkNLFLSkLQHGtQ S324
TRF1 (mouse) RSHKNALSQLKHRRA S310
TRF1 (rat) RSHKNALsPLKSRRL S310-p
K325-ub
HkNLFLSkLQHGtQQ
0 2
TRF1 (human) HkNLFLSkLQHGtQQ K325-ub
TRF1 (mouse) under review -
TRF1 (rat) under review -
T330-p
LSkLQHGtQQQDLNK
0 1
TRF1 (human) LSkLQHGtQQQDLNK T330-p
TRF1 (mouse) LSQLKHRRAPSDFSR R316
TRF1 (rat) LsPLKSRRLQPDFNR R316
T344-p
KKERRVGtPQsTKKK
Upstream
Downstream
1 1
Effects on Modified Protein
  • phosphorylation
Kinase, in vitro:
  • CDK1 (human)
TRF1 (human) KKERRVGtPQsTKKK T344-p
TRF1 (mouse) RNEARTGTLQCETTM T330
TRF1 (rat) RNEARTGTLQCEIAT T330
S347-p
RRVGtPQsTKKKKES
0 2
TRF1 (human) RRVGtPQsTKKKKES S347-p
TRF1 (mouse) RTGTLQCETTMERNR E334
TRF1 (rat) RTGTLQCEIATKRNR E334
T358-p
KKESRRAtESRIPVS
0 1
TRF1 (human) KKESRRAtESRIPVS T358-p
TRF1 (mouse) ERNRRTSGRNRLCVS G345
TRF1 (rat) KRNRRTSGGNRLRIS G345
S367-p
SRIPVSKsQPVtPEK
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • KU-55933
  • MG132
  • NU7026
TRF1 (human) SRIPVSKsQPVtPEK S367-p
TRF1 (mouse) NRLCVSENQPDTDDK N354
TRF1 (rat) NRLRISKNQPDTNEK N354
T371-p
VSKsQPVtPEKHRAR
Upstream
Downstream
4 9
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, induced
  • cell cycle regulation
  • cell growth, induced
  • chromatin organization, altered
Kinase, in vitro:
  • CDK1 (human)
Putative in vivo kinases:
  • CDK1 (human)
Regulatory protein:
  • 53BP1 (human)
  • BRCA1 (human)
  • RIF1 (human)
Treatment
  • CGP74514A
  • cycloheximide
  • DMSO
  • KCl
  • mirin
  • nocodazole
  • okadaic_acid
  • seliciclib
TRF1 (human) VSKsQPVtPEKHRAR T371-p
TRF1 (mouse) VSENQPDTDDKSGRR T358
TRF1 (rat) ISKNQPDTNEKHGRR T358
K397-ub
NLRSGVRkYGEGNWS
0 1
TRF1 (human) NLRSGVRkYGEGNWS K397-ub
TRF1 (mouse) ILKCGVKKYGEGNWA K384
TRF1 (rat) SLKCGVRKYGEGNWA K384
K411-ub
SKILLHYkFNNRTSV
0 1
TRF1 (human) SKILLHYkFNNRTSV K411-ub
TRF1 (mouse) AKILSHYKFNNRTSV K398
TRF1 (rat) AKILSHYKFNNRTSV K398
S434-p
MKKLKLIssDsED__
0 5
TRF1 (human) MKKLKLIssDsED__ S434-p
TRF1 (mouse) MKRLKLIs_______ S421-p
TRF1 (rat) MRRLRLIS_______ S421
S435-p
KKLKLIssDsED___
Upstream
Downstream
1 5
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • PLK1 (human)
Putative in vivo kinases:
  • PLK1 (human)
TRF1 (human) KKLKLIssDsED___ S435-p
TRF1 (mouse) gap -
TRF1 (rat) gap -
S437-p
LKLIssDsED_____
0 5
TRF1 (human) LKLIssDsED_____ S437-p
TRF1 (mouse) gap -
TRF1 (rat) gap -