Other Species / Isoforms
  SMAD1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S11-p
TSLFSFTsPAVKRLL
0 2
SMAD1 (human) TSLFSFTsPAVKRLL S11-p
SMAD1 (mouse) TSLFSFTSPAVKRLL S11
SMAD1 (rat) TSLFSFTSPAVKRLL S11
K116-ub
CEFPFGSkQkEVCIN
1 0
SMAD1 (human) CEFPFGSkQkEVCIN K116-ub
SMAD1 (mouse) CEFPFGSKQKEVCIN K116
SMAD1 (rat) CEFPFGSKQKEVCIN K116
K118-ub
FPFGSkQkEVCINPY
1 1
SMAD1 (human) FPFGSkQkEVCINPY K118-ub
SMAD1 (mouse) FPFGSKQKEVCINPY K118
SMAD1 (rat) FPFGSKQKEVCINPY K118
S132-p
YHYKRVEsPVLPPVL
0 10
SMAD1 (human) YHYKRVEsPVLPPVL S132-p
SMAD1 (mouse) YHYKRVEsPVLPPVL S132-p
SMAD1 (rat) YHYKRVESPVLPPVL S132
S144-p
PVLVPRHsEyNPQHS
0 1
SMAD1 (human) PVLVPRHsEyNPQHS S144-p
SMAD1 (mouse) PVLVPRHsEYNPQHS S144-p
SMAD1 (rat) PVLVPRHSEYNPQHS S144
Y146-p
LVPRHsEyNPQHSLL
0 1
SMAD1 (human) LVPRHsEyNPQHSLL Y146-p
SMAD1 (mouse) LVPRHsEYNPQHSLL Y146
SMAD1 (rat) LVPRHSEYNPQHSLL Y146
S187-p
NSHPFPHsPNSSYPN
Upstream
Downstream
4 0
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • CDK8 (human)
  • CDK9 (human)
  • ERK2 (human)
SMAD1 (human) NSHPFPHsPNSSYPN S187-p
SMAD1 (mouse) NSHPFPHSPNSSYPN S187
SMAD1 (rat) HSHPFPQSPNSSYPN S187
S195-p
PNSSYPNsPGSSSSt
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • CDK8 (human)
  • CDK9 (human)
  • ERK2 (human)
Treatment
  • EGF
  • HGF
  • serum_starvation
  • wortmannin
SMAD1 (human) PNSSYPNsPGSSSSt S195-p
SMAD1 (mouse) PNSSYPNSPGGSSST S195
SMAD1 (rat) PNSSYPNSPGSSSST S195
T202-p
sPGSSSStYPHsPTS
Upstream
1 0
Kinase, in vitro:
  • GSK3B (human)
SMAD1 (human) sPGSSSStYPHsPTS T202-p
SMAD1 (mouse) SPGGSSSTYPHSPTS T202
SMAD1 (rat) SPGSSSSTYPHSPTS T202
S206-p
SSStYPHsPTSSDPG
Upstream
Downstream
3 0
SMAD1 (human)
S206-p
SMAD1 (mouse)
S206-p
SMAD1 (rat)
S206-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • CDK8 (human)
  • CDK9 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • CDK7 (human)
  • CDK8 (human)
  • CDK9 (human)
Regulatory protein:
  • FOXO4 (human)
  • SMAD1 (mouse)
  • SMAD4 (human)
  • SMURF1 (mouse)
Treatment
  • alvocidib
  • amanitin
  • BMP2
  • EGF
  • FGF1
  • HGF
  • hypertonic_buffer
  • insulin
  • MG132
  • SB203580
  • serum_starvation
  • SP600125
  • TGF-beta
  • U0126
  • UV
  • wortmannin
SMAD1 (human) SSStYPHsPTSSDPG S206-p
SMAD1 (mouse) SSSTYPHSPTSSDPG S206
SMAD1 (rat) SSSTYPHSPTSSDPG S206
S214-p
PTSSDPGsPFQMPAD
Upstream
Downstream
3 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • CDK8 (human)
  • CDK9 (human)
  • ERK2 (human)
Treatment
  • EGF
  • HGF
  • serum_starvation
  • wortmannin
SMAD1 (human) PTSSDPGsPFQMPAD S214-p
SMAD1 (mouse) PTSSDPGSPFQMPAD S214
SMAD1 (rat) PTSSDPGSPFQMPAD S214
S239-p
DPMTQDGsQPMDTNM
Upstream
Downstream
1 0
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • apoptosis, induced
  • carcinogenesis, inhibited
  • transcription, induced
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • adriamycin
  • caffeine
SMAD1 (human) DPMTQDGsQPMDTNM S239-p
SMAD1 (mouse) DPMAQDGSQPMDTNM S239
SMAD1 (rat) DPMAQDGSQPMDTNM S239
K269-ub
AVAYEEPkHWCSIVY
1 0
SMAD1 (human) AVAYEEPkHWCSIVY K269-ub
SMAD1 (mouse) AVAYEEPKHWCSIVY K269
SMAD1 (rat) AVAYEEPKHWCSIVY K272
T300
SVLVDGFTDPSNNKN
0 1
SMAD1 (human) SVLVDGFTDPSNNKN T300
SMAD1 (mouse) SVLVDGFTDPSNNKN T300
SMAD1 (rat) SVLVDGFtDPsNNKN T303-p
S303
VDGFTDPSNNKNRFC
0 1
SMAD1 (human) VDGFTDPSNNKNRFC S303
SMAD1 (mouse) VDGFTDPSNNKNRFC S303
SMAD1 (rat) VDGFtDPsNNKNRFC S306-p
T322-p
SNVNRNStIENTRRH
Upstream
Downstream
2 4
Effects on Modified Protein
  • activity, inhibited
  • phosphorylation
Kinase, in vitro:
  • HGK (human)
  • MINK (human)
  • TNIK (human)
Putative in vivo kinases:
  • HGK (human)
  • MINK (human)
  • TNIK (human)
Treatment
  • okadaic_acid
SMAD1 (human) SNVNRNStIENTRRH T322-p
SMAD1 (mouse) SNVNRNStIENTRRH T322-p
SMAD1 (rat) SNVNRNStIENTRRH T325-p
S456-p
KVLTQMGsPHNPIss
1 1
SMAD1 (human) KVLTQMGsPHNPIss S456-p
SMAD1 (mouse) KVLTQMGSPHNPIss S456
SMAD1 (rat) KVLTQMGsPHNPISs S459-p
S462-p
GsPHNPIssVs____
Upstream
Downstream
2 8
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • BMPR1B (human)
Putative in vivo kinases:
  • BMPR1B (human)
Treatment
  • EGF
  • HGF
  • serum_starvation
  • wortmannin
SMAD1 (human) GsPHNPIssVs____ S462-p
SMAD1 (mouse) GSPHNPIssVs____ S462-p
SMAD1 (rat) GsPHNPISsVs____ S465
S463-p
sPHNPIssVs_____
Upstream
Downstream
10 71
SMAD1 (human)
S463-p
SMAD1 (mouse)
S463-p
SMAD1 (rat)
S466-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • BMPR1B (human)
Putative in vivo kinases:
  • BMPR1B (human)
Regulatory protein:
  • BMP2 (human)
  • KIF1B (human)
  • TOB1 (human)
  • TRRAP (human)
Treatment
  • activin
  • BMP2
  • EGF
  • FGF2
  • heregulin
  • HGF
  • IGF-1
  • serum_starvation
  • serum_withdrawal
  • starvation_medium
  • wortmannin
SMAD1 (human) sPHNPIssVs_____ S463-p
SMAD1 (mouse) SPHNPIssVs_____ S463-p
SMAD1 (rat) sPHNPISsVs_____ S466-p
S465-p
HNPIssVs_______
Upstream
Downstream
10 79
SMAD1 (human)
S465-p
SMAD1 (mouse)
S465-p
SMAD1 (rat)
S468-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • BMPR1B (human)
Putative in vivo kinases:
  • BMPR1B (human)
Regulatory protein:
  • BMP2 (human)
  • KIF1B (human)
  • TOB1 (human)
  • TRRAP (human)
Treatment
  • activin
  • BMP2
  • EGF
  • FGF2
  • heregulin
  • HGF
  • IGF-1
  • serum_starvation
  • serum_withdrawal
  • starvation_medium
  • Su11274
  • wortmannin
SMAD1 (human) HNPIssVs_______ S465-p
SMAD1 (mouse) HNPIssVs_______ S465-p
SMAD1 (rat) HNPISsVs_______ S468-p