Other Species / Isoforms
  DYRK1A (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S14
TSACKPSsVRLAPSF
0 1
DYRK1A (human) TSACKPSsVRLAPSF S14
DYRK1A iso2 (human) TSACKPSSVRLAPSF S14
DYRK1A iso4 (human) TSACKPSSVRLAPSF S14
DYRK1A (mouse) TSACKPSSVRLAPSF S14
DYRK1A (rat) TSACKPSSVRLAPSF S14
DYRK1A (rabbit) gap -
S22
VRLAPSFsFHAAGLQ
0 2
DYRK1A (human) VRLAPSFsFHAAGLQ S22
DYRK1A iso2 (human) VRLAPSFSFHAAGLQ S22
DYRK1A iso4 (human) VRLAPSFSFHAAGLQ S22
DYRK1A (mouse) VRLAPSFsFHAAGLQ S22
DYRK1A (rat) VRLAPSFSFHAAGLQ S22
DYRK1A (rabbit) gap -
Y40
QMPHSHQySDRRQPN
0 1
DYRK1A (human) QMPHSHQySDRRQPN Y40
DYRK1A iso2 (human) QMPHSHQYSDRRQPN Y40
DYRK1A iso4 (human) QMPHSHQYSDRRQPN Y40
DYRK1A (mouse) QMPHSHQYSDRRQPs Y40
DYRK1A (rat) QMPHSHQYSDRRQPN Y40
DYRK1A (rabbit) gap -
N47
ySDRRQPNISDQQVS
0 1
DYRK1A (human) ySDRRQPNISDQQVS N47
DYRK1A iso2 (human) YSDRRQPNISDQQVS N47
DYRK1A iso4 (human) YSDRRQPNISDQQVS N47
DYRK1A (mouse) YSDRRQPsIsDQQVS S47
DYRK1A (rat) YSDRRQPNISDQQVS N47
DYRK1A (rabbit) _____QPSISDQQVS S3
S49
DRRQPNISDQQVSAL
0 1
DYRK1A (human) DRRQPNISDQQVSAL S49
DYRK1A iso2 (human) DRRQPNISDQQVSAL S49
DYRK1A iso4 (human) DRRQPNISDQQVSAL S49
DYRK1A (mouse) DRRQPsIsDQQVSAL S49
DYRK1A (rat) DRRQPNISDQQVSAL S49
DYRK1A (rabbit) ___QPSISDQQVSAL S5
S57
DQQVSALSYSDQIQQ
0 1
DYRK1A (human) DQQVSALSYSDQIQQ S57
DYRK1A iso2 (human) DQQVSALsYSDQIQQ S57
DYRK1A iso4 (human) DQQVSALSYSDQIQQ S57
DYRK1A (mouse) DQQVSALPYSDQIQQ P57
DYRK1A (rat) DQQVSALSYSDQIQQ S57
DYRK1A (rabbit) DQQVSALPYSDQIQQ P13
Y104
SVDLIKTYKHINEVy
0 1
DYRK1A (human) SVDLIKTYKHINEVy Y104
DYRK1A iso2 (human) SVDLIKTYKHINEVY Y95
DYRK1A iso4 (human) SVDLIKTYKHINEVY Y104
DYRK1A (mouse) SVDLIKTYKHINEVy Y104
DYRK1A (rat) SVDLIKTyKHINEVy Y104
DYRK1A (rabbit) gap -
Y111
YKHINEVyYAKKKRR
Upstream
0 26
Treatment
  • U0126
DYRK1A (human) YKHINEVyYAKKKRR Y111
DYRK1A iso2 (human) YKHINEVYYAKKKRR Y102
DYRK1A iso4 (human) YKHINEVYYAKKKRR Y111
DYRK1A (mouse) YKHINEVyYAKKKRR Y111
DYRK1A (rat) yKHINEVyYAKKKRR Y111
DYRK1A (rabbit) gap -
S127
QQGQGDDsSHKKERK
0 1
DYRK1A (human) QQGQGDDsSHKKERK S127
DYRK1A iso2 (human) QQGQGDDSSHKKERK S118
DYRK1A iso4 (human) QQGQGDDSSHKKERK S127
DYRK1A (mouse) QQGQGDDSSHKKERK S127
DYRK1A (rat) QQGQGDDSSHKKERK S127
DYRK1A (rabbit) gap -
Y136
HKKERKVyNDGYDDD
0 2
DYRK1A (human) HKKERKVyNDGYDDD Y136
DYRK1A iso2 (human) HKKERKVYNDGYDDD Y127
DYRK1A iso4 (human) HKKERKVYNDGYDDD Y136
DYRK1A (mouse) HKKERKVYNDGYDDD Y136
DYRK1A (rat) HKKERKVYNDGYDDD Y136
DYRK1A (rabbit) gap -
Y145
DGYDDDNyDyIVKNG
Upstream
Downstream
1 905
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
  • cell differentiation, altered
Regulatory protein:
  • ZAP70 (human)
DYRK1A (human) DGYDDDNyDyIVKNG Y145
DYRK1A iso2 (human) DGYDDDNyDYIVKNG Y136
DYRK1A iso4 (human) DGYDDDNyDyIVKNG Y145
DYRK1A (mouse) DGYDDDNyDyIVKNG Y145
DYRK1A (rat) DGYDDDNyDyIVKNG Y145
DYRK1A (rabbit) gap -
Y147
YDDDNyDyIVKNGEK
Downstream
1 20
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
  • cell differentiation, altered
DYRK1A (human) YDDDNyDyIVKNGEK Y147
DYRK1A iso2 (human) YDDDNyDYIVKNGEK Y138
DYRK1A iso4 (human) YDDDNyDyIVKNGEK Y147
DYRK1A (mouse) YDDDNyDyIVKNGEK Y147
DYRK1A (rat) YDDDNyDyIVKNGEK Y147
DYRK1A (rabbit) gap -
Y159
GEKWMDRyEIDSLIG
0 4
DYRK1A (human) GEKWMDRyEIDSLIG Y159
DYRK1A iso2 (human) GEKWMDRYEIDSLIG Y150
DYRK1A iso4 (human) GEKWMDRYEIDSLIG Y159
DYRK1A (mouse) GEKWMDRYEIDSLIG Y159
DYRK1A (rat) GEKWMDRYEIDSLIG Y159
DYRK1A (rabbit) QRRWMDRYEIDSLIG Y41
Y219
KHDTEMKYYIVHLKR
1 0
DYRK1A (human) KHDTEMKYYIVHLKR Y219
DYRK1A iso2 (human) KHDTEMKYYIVHLKR Y210
DYRK1A iso4 (human) KHDTEMKYYIVHLKR Y219
DYRK1A (mouse) KHDTEMKYYIVHLKR Y219
DYRK1A (rat) KHDTEMKyYIVHLKR Y219
DYRK1A (rabbit) RHDTEMKYYIVHLKI Y76
Y319
CQLGQRIyQyIQsRF
2 188
DYRK1A (human) CQLGQRIyQyIQsRF Y319
DYRK1A iso2 (human) CQLGQRIYQYIQSRF Y310
DYRK1A iso4 (human) CQLGQRIyQyIQSRF Y319
DYRK1A (mouse) CQLGQRIyQyIQsRF Y319
DYRK1A (rat) CQLGQRIyQyIQsRF Y319
DYRK1A (rabbit) gap -
Y321
LGQRIyQyIQsRFYR
Upstream
6 3806
Regulatory protein:
  • EGFR (human)
Treatment
  • ephrin_B1
  • LRRK2-IN-1
  • metastatic potential
DYRK1A (human) LGQRIyQyIQsRFYR Y321
DYRK1A iso2 (human) LGQRIYQYIQSRFYR Y312
DYRK1A iso4 (human) LGQRIyQyIQSRFYR Y321
DYRK1A (mouse) LGQRIyQyIQsRFYR Y321
DYRK1A (rat) LGQRIyQyIQsRFYR Y321
DYRK1A (rabbit) gap -
S324
RIyQyIQsRFYRSPE
0 394
DYRK1A (human) RIyQyIQsRFYRSPE S324
DYRK1A iso2 (human) RIYQYIQSRFYRSPE S315
DYRK1A iso4 (human) RIyQyIQSRFYRSPE S324
DYRK1A (mouse) RIyQyIQsRFYRSPE S324
DYRK1A (rat) RIyQyIQsRFYRSPE S324
DYRK1A (rabbit) gap -
T466
MLDYDPKtRIQPYYA
0 1
DYRK1A (human) MLDYDPKtRIQPYYA T466
DYRK1A iso2 (human) MLDYDPKTRIQPYYA T457
DYRK1A iso4 (human) MLDYDPKTRIQPYYA T466
DYRK1A (mouse) MLDYDPKtRIQPYYA T466
DYRK1A (rat) MLDYDPKTRIQPYYA T466
DYRK1A (rabbit) gap -
S529
SNSGRARsDPtHQHR
Upstream
Downstream
2 6
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Putative in vivo kinases:
  • DYRK1A (human)
Treatment
  • FGF2
  • harmine
  • MG132_withdrawal
  • SB216763
DYRK1A (human) SNSGRARsDPtHQHR S529
DYRK1A iso2 (human) SNSGRARSDPTHQHR S520
DYRK1A iso4 (human) gap -
DYRK1A (mouse) SNSGRARsDPTHQHR S529
DYRK1A (rat) SNSGRARSDPTHQHR S529
DYRK1A (rabbit) gap -
T532
GRARsDPtHQHRHsG
0 1
DYRK1A (human) GRARsDPtHQHRHsG T532
DYRK1A iso2 (human) GRARSDPTHQHRHSG T523
DYRK1A iso4 (human) gap -
DYRK1A (mouse) GRARsDPTHQHRHsG T532
DYRK1A (rat) GRARSDPTHQHRHSG T532
DYRK1A (rabbit) gap -
S538
PtHQHRHsGGHFtAA
0 7
DYRK1A (human) PtHQHRHsGGHFtAA S538
DYRK1A iso2 (human) PTHQHRHSGGHFTAA S529
DYRK1A iso4 (human) gap -
DYRK1A (mouse) PTHQHRHsGGHFAAA S538
DYRK1A (rat) PTHQHRHSGGHFAAA S538
DYRK1A (rabbit) gap -
T543
RHsGGHFtAAVQAMD
0 1
DYRK1A (human) RHsGGHFtAAVQAMD T543
DYRK1A iso2 (human) RHSGGHFTAAVQAMD T534
DYRK1A iso4 (human) gap -
DYRK1A (mouse) RHsGGHFAAAVQAMD A543
DYRK1A (rat) RHSGGHFAAAVQAMD A543
DYRK1A (rabbit) gap -
T553
VQAMDCEtHsPQVRQ
0 1
DYRK1A (human) VQAMDCEtHsPQVRQ T553
DYRK1A iso2 (human) VQAMDCETHSPQVRQ T544
DYRK1A iso4 (human) gap -
DYRK1A (mouse) VQAMDCETHsPQVRQ T553
DYRK1A (rat) VQAMDCETHSPQVRQ T553
DYRK1A (rabbit) gap -
S555
AMDCEtHsPQVRQQF
0 5
DYRK1A (human) AMDCEtHsPQVRQQF S555
DYRK1A iso2 (human) AMDCETHSPQVRQQF S546
DYRK1A iso4 (human) gap -
DYRK1A (mouse) AMDCETHsPQVRQQF S555
DYRK1A (rat) AMDCETHSPQVRQQF S555
DYRK1A (rabbit) gap -
Y705
MDVNLTVysNPRQET
0 5
DYRK1A (human) MDVNLTVysNPRQET Y705
DYRK1A iso2 (human) MDVNLTVYSNPRQET Y696
DYRK1A iso4 (human) gap -
DYRK1A (mouse) MDVNLTVYSNPRQET Y705
DYRK1A (rat) MDVNLTVYSNPRQET Y705
DYRK1A (rabbit) gap -
S706
DVNLTVysNPRQETG
0 1
DYRK1A (human) DVNLTVysNPRQETG S706
DYRK1A iso2 (human) DVNLTVYSNPRQETG S697
DYRK1A iso4 (human) gap -
DYRK1A (mouse) DVNLTVYSNPRQETG S706
DYRK1A (rat) DVNLTVYSNPRQETG S706
DYRK1A (rabbit) gap -
S748
QGADREEsPMTGVCV
Upstream
0 18
Treatment
  • nocodazole
  • thymidine
DYRK1A (human) QGADREEsPMTGVCV S748
DYRK1A iso2 (human) QGADREESPMTGVCV S739
DYRK1A iso4 (human) gap -
DYRK1A (mouse) QGADREEsPMTGVCV S748
DYRK1A (rat) QGADREESPMTGVCV S748
DYRK1A (rabbit) gap -
S758
TGVCVQQsPVAsS__
Upstream
0 33
Treatment
  • nocodazole
  • thymidine
DYRK1A (human) TGVCVQQsPVAsS__ S758
DYRK1A iso2 (human) TGVCVQQSPVASS__ S749
DYRK1A iso4 (human) gap -
DYRK1A (mouse) TGVCVQQsPVASS__ S758
DYRK1A (rat) TGVCVQQSPVASS__ S758
DYRK1A (rabbit) gap -
S762
VQQsPVAsS______
0 1
DYRK1A (human) VQQsPVAsS______ S762
DYRK1A iso2 (human) VQQSPVASS______ S753
DYRK1A iso4 (human) gap -
DYRK1A (mouse) VQQsPVASS______ S762
DYRK1A (rat) VQQSPVASS______ S762
DYRK1A (rabbit) gap -