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Site Information |
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AFAPPRSsPCASSTP SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 450157 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
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Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on PR: | |
Effects of modification on biological processes: | |
Induce interaction with: |
References | |
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Hagan CR, Knutson TP, Lange CA (2013) A Common Docking Domain in Progesterone Receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cells. Nucleic Acids Res 41, 8926-42
23921636 Curated Info |
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Busia L, Faus H, Hoffmann J, Haendler B (2011) The antiprogestin Lonaprisan inhibits breast cancer cell proliferation by inducing p21 expression. Mol Cell Endocrinol 333, 37-46
21138753 Curated Info |
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Wardell SE, Narayanan R, Weigel NL, Edwards DP (2010) Partial Agonist Activity of the Progesterone Receptor Antagonist RU486 Mediated by an Amino-Terminal Domain Coactivator and Phosphorylation of Serine400. Mol Endocrinol 24, 335-45
20008003 Curated Info |
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Faivre EJ, Daniel AR, Hillard CJ, Lange CA (2008) Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors. Mol Endocrinol 22, 823-37
18202149 Curated Info |
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Knotts TA, et al. (2001) Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites. J Biol Chem 276, 8475-83
11110801 Curated Info |
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Beck CA, et al. (1996) Stoichiometry and site-specific phosphorylation of human progesterone receptor in native target cells and in the baculovirus expression system. J Biol Chem 271, 19546-55
8702648 Curated Info |
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Takimoto GS, et al. (1996) Role of phosphorylation on DNA binding and transcriptional functions of human progesterone receptors. J Biol Chem 271, 13308-16
8662865 Curated Info |
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Zhang Y, et al. (1995) Identification of a group of Ser-Pro motif hormone-inducible phosphorylation sites in the human progesterone receptor. Mol Endocrinol 9, 1029-40
7476977 Curated Info |