Ser676
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.7
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser676  -  PR (human)

Site Information
LSQRFTFsPGQDIQL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450154

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 2 ) , HeLa (cervical) ( 2 ) , SF9 ( 1 )

Upstream Regulation
Kinases, in vitro:
CDK2 (human) ( 1 )
Treatments:
progestin_R5020 ( 1 )

Downstream Regulation
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Knotts TA, et al. (2001) Identification of a phosphorylation site in the hinge region of the human progesterone receptor and additional amino-terminal phosphorylation sites. J Biol Chem 276, 8475-83
11110801   Curated Info

2

Takimoto GS, et al. (1996) Role of phosphorylation on DNA binding and transcriptional functions of human progesterone receptors. J Biol Chem 271, 13308-16
8662865   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.