Ser857
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Home > Phosphorylation Site Page: > Ser857  -  DYN1 (rat)

Site Information
AsPSRPEsPRPPFDL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455277

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 3 ) , mass spectrometry ( 2 , 3 ) , phospho-antibody ( 1 ) , western blotting ( 1 , 3 )
Relevant cell line - cell type - tissue:
'brain, brainstem' ( 2 ) , 'brain, cerebellum' ( 2 ) , 'brain, cerebral cortex' ( 2 ) , 'brain, hippocampus' ( 1 ) , brain ( 3 ) , neuron:synaptosome ( 3 )

Upstream Regulation
Treatments:
depolarization ( 3 ) , electrical_stimulation ( 1 ) , long-term_potentiation ( 1 )

Downstream Regulation
Effects of modification on DYN1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
amphiphysin (human) ( 1 )

References 

1

Xie W, et al. (2012) Activity-dependent phosphorylation of dynamin 1 at serine 857. Biochemistry 51, 6786-96
22857010   Curated Info

2

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

3

Chan LS, Hansra G, Robinson PJ, Graham ME (2010) Differential phosphorylation of dynamin I isoforms in subcellular compartments demonstrates the hidden complexity of phosphoproteomes. J Proteome Res 9, 4028-37
20560669   Curated Info