Ser197

Site Information
VTRKsAPssPTLDCE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 481533

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 3 , 4 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 4 ) , HeLa (cervical) ( 3 ) , HMLER ('stem, breast cancer') [CXCR4 (human), knockdown] ( 1 ) , HMLER ('stem, breast cancer') ( 1 )

References
1	Yi T, et al. (2014) Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells. Proc Natl Acad Sci U S A 111, E2182-90 24782546 Curated Info
2	Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21 23312004 Curated Info
3	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info
4	Gauci S, et al. (2009) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal Chem 81, 4493-501 19413330 Curated Info