Thr390
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Home > Phosphorylation Site Page: > Thr390  -  p70S6K (mouse)

Site Information
DSKFTRQtPVDsPDD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450099

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 3 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 3 ) , 'stem, mesenchymal' ( 1 ) , bone marrow ( 1 )

Upstream Regulation
Treatments:
insulin ( 3 )

References 

1

Dai Q, et al. (2017) mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression. Cell Death Differ 24, 1886-1899
28686577   Curated Info

2

Cam M, et al. (2014) p53/TAp63 and AKT Regulate Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling through Two Independent Parallel Pathways in the Presence of DNA Damage. J Biol Chem 289, 4083-94
24366874   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info