Ser443
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.7
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser443  -  EPB41L3 (human)

Site Information
KRYTMSRsLDGEVGT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 486559

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 3 , 4 , 6 )
Disease tissue studied:
HER2 positive breast cancer ( 1 ) , luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 ) , breast cancer, surrounding tissue ( 1 ) , breast cancer, triple negative ( 1 ) , lung cancer ( 3 , 4 ) , non-small cell lung cancer ( 4 ) , non-small cell lung adenocarcinoma ( 3 )
Relevant cell line - cell type - tissue:
breast ( 1 ) , H2009 (pulmonary) ( 4 ) , H2887 (pulmonary) ( 4 ) , HCC1359 (pulmonary) ( 4 ) , HCC4006 (pulmonary) ( 4 ) , HCC827 (pulmonary) ( 4 ) , LCLC-103H (pulmonary) ( 4 ) , LOU-NH91 (squamous) ( 4 ) , lung ( 3 ) , NCI-H1395 (pulmonary) ( 4 ) , NCI-H1568 (pulmonary) ( 4 ) , NCI-H2030 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 4 , 6 ) , NCI-H647 (pulmonary) ( 4 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

3

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

4

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

5

Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773   Curated Info

6

Nagano K, et al. (2009) Phosphoproteomic analysis of distinct tumor cell lines in response to nocodazole treatment. Proteomics 9, 2861-74
19415658   Curated Info