Tyr78
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Home > Phosphorylation Site Page: > Tyr78  -  C/EBP-beta (human)

Site Information
RAIDFsPyLEPLGAP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 9397201

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 ) , chronic myelogenous leukemia ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , 293T (epithelial) ( 1 ) , K562 (erythroid) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Abl (human) ( 1 ) , Arg (human) ( 1 )
Treatments:
imatinib ( 1 )

Downstream Regulation
Effects of modification on C/EBP-beta:
protein stabilization ( 1 )
Effects of modification on biological processes:
apoptosis, altered ( 1 ) , cell cycle regulation ( 1 ) , transcription, induced ( 1 )

References 

1

Li X, et al. (2009) Non-receptor tyrosine kinases c-Abl and Arg regulate the activity of C/EBPbeta. J Mol Biol 391, 729-43
19563810   Curated Info