Ser156
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Home > Phosphorylation Site Page: > Ser156  -  CREM (mouse)

Site Information
PKIEEEKsEEEGTPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450064

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 , 2 ) , mutation of modification site ( 1 ) , phosphoamino acid analysis ( 1 , 2 ) , phosphopeptide mapping ( 1 , 2 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 , 2 )

Upstream Regulation
Putative in vivo kinases:
CDK1 (mouse) ( 1 )
Kinases, in vitro:
CDK1 (mouse) ( 1 , 2 ) , CK1A (human) ( 2 ) , CK2A1 (human) ( 2 )

Downstream Regulation
Effects of modification on CREM:
activity, inhibited ( 1 )
Effects of modification on biological processes:
transcription, altered ( 1 )

References 

1

de Groot RP, Derua R, Goris J, Sassone-Corsi P (1993) Phosphorylation and negative regulation of the transcriptional activator CREM by p34cdc2. Mol Endocrinol 7, 1495-50
8114763   Curated Info

2

de Groot RP, et al. (1993) Multiple and cooperative phosphorylation events regulate the CREM activator function. EMBO J 12, 3903-11
8404858   Curated Info

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