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Site Information |
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SLAWLSDsPLFDLIk SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 450021 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
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Downstream Regulation | |
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Effects of modification on Rb: | |
Effects of modification on biological processes: | |
Induce interaction with: |
References | |
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Rousset-Roman A, Rebolloso-Gómez Y, Olivares-Illana V (2019) Expression and purification of the recombinant full-length retinoblastoma protein and characterisation of its interaction with the oncoprotein HDM2. Protein Expr Purif 162, 62-66
31163228 Curated Info |
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Cao L, Zhang L, Zhao X, Zhang Y (2016) A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells. PLoS One 11, e0161025
27525972 Curated Info |
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Mitra R, et al. (2012) Sodium butyrate modulates pRb phosphorylation and induces cell death in human vestibular schwannomas in vitro. Indian J Exp Biol 50, 19-27
22279936 Curated Info |
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Delston RB, et al. (2011) p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis. Oncogene 30, 588-99
20871633 Curated Info |
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Ma D, Zhou P, Harbour JW (2003) Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb. J Biol Chem 278, 19358-66
12646568 Curated Info |