Ser612
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Home > Phosphorylation Site Page: > Ser612  -  CTCF (chicken)

Site Information
KKEDssDsEENAEPD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448305

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 , 2 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 , 2 ) , phosphoamino acid analysis ( 2 ) , phosphopeptide mapping ( 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 , 2 ) , HD3 ( 2 )

Upstream Regulation
Putative in vivo kinases:
CK2A1 (human) ( 1 )
Kinases, in vitro:
CK2A1 (human) ( 2 )

Downstream Regulation
Effects of modification on CTCF:
activity, inhibited ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 2 ) , transcription, altered ( 2 ) , transcription, induced ( 1 )

References 

1

El-Kady A, Klenova E (2005) Regulation of the transcription factor, CTCF, by phosphorylation with protein kinase CK2. FEBS Lett 579, 1424-34
15733852   Curated Info

2

Klenova EM, et al. (2001) Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF. Mol Cell Biol 21, 2221-34
11238955   Curated Info

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