Ser229

Site Information
HAEVLVKsNNLTDRI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 486445

In vivo Characterization
Methods used to characterize site in vivo:	2D analysis ( 1 ) , [32P] ATP in vitro ( 1 ) , electrophoretic mobility shift ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	HeLa (cervical) ( 1 ) , MEF (fibroblast) ( 1 ) , SKBr3 (breast cell) ( 1 )

Downstream Regulation
Effects of modification on CARM1:	enzymatic activity, inhibited ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:	transcription, inhibited ( 1 )
Inhibit interaction with:	CARM1 (mouse) ( 1 )

References
1	Higashimoto K, et al. (2007) Phosphorylation-mediated inactivation of coactivator-associated arginine methyltransferase 1. Proc Natl Acad Sci U S A 104, 12318-23 17640894 Curated Info