Thr7
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Home > Phosphorylation Site Page: > Thr7  -  MCM4 (human)

Site Information
_MssPAstPsrrGsr   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 450000

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 4 ) , mass spectrometry ( 1 , 2 ) , phospho-antibody ( 3 , 4 ) , western blotting ( 4 )
Disease tissue studied:
melanoma skin cancer ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on MCM4:
activity, inhibited ( 4 )

References 

1

Huang H, et al. (2016) Simultaneous Enrichment of Cysteine-containing Peptides and Phosphopeptides Using a Cysteine-specific Phosphonate Adaptable Tag (CysPAT) in Combination with titanium dioxide (TiO2) Chromatography. Mol Cell Proteomics 15, 3282-3296
27281782   Curated Info

2

Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. Mol Cell Proteomics 14, 1599-615
25850435   Curated Info

3

Komamura-Kohno Y, et al. (2006) Site-specific phosphorylation of MCM4 during the cell cycle in mammalian cells. FEBS J 273, 1224-39
16519687   Curated Info

4

Ishimi Y, et al. (2003) Identification of MCM4 as a target of the DNA replication block checkpoint system. J Biol Chem 278, 24644-50
12714602   Curated Info