Lys139
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Home > Ubiquitylation Site Page: > Lys139  -  p53 (human)

Site Information
kMFCQLAkTCPVQLW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 486295

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on p53:
intracellular localization ( 1 ) , protein degradation ( 1 )

References 

1

Nie L, Sasaki M, Maki CG (2007) Regulation of p53 nuclear export through sequential changes in conformation and ubiquitination. J Biol Chem 282, 14616-25
17371868   Curated Info