Lys101
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Home > Ubiquitylation Site Page: > Lys101  -  p53 (human)

Site Information
SSSVPsQkTYQGsYG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 486292

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 3 ) , mass spectrometry ( 1 , 2 ) , mutation of modification site ( 3 ) , western blotting ( 3 )
Disease tissue studied:
bone cancer ( 3 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on p53:
intracellular localization ( 3 ) , protein degradation ( 3 )

References 

1

Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell 44, 325-40
21906983   Curated Info

2

Wagner SA, et al. (2011) A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles. Mol Cell Proteomics 10, M111.013284
21890473   Curated Info

3

Nie L, Sasaki M, Maki CG (2007) Regulation of p53 nuclear export through sequential changes in conformation and ubiquitination. J Biol Chem 282, 14616-25
17371868   Curated Info