Lys6

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Home > Ubiquitylation Site Page: > Lys6 - ENaC-gamma (rat)

Site Information
__MAPGEkIkAkIkk SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 486250

In vivo Characterization
Methods used to characterize site in vivo:	electrophoretic mobility shift ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , 3T3 (fibroblast) ( 1 ) , COS7 (fibroblast) ( 1 ) , MDCK (epithelial) ( 1 ) , oocyte ( 1 )

Downstream Regulation
Effects of modification on ENaC-gamma:	intracellular localization ( 1 ) , protein degradation ( 1 ) , receptor recycling, inhibited ( 1 )

References
1	Staub O, et al. (1997) Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination. EMBO J 16, 6325-36 9351815 Curated Info

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