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Home > Ubiquitylation Site Page: > Lys21  -  IkB-alpha (human)

Site Information
EGPRDGLkkERLLDD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 485773

Downstream Regulation
Effects of modification on IkB-alpha:
protein degradation ( 1 )



Rodriguez MS, et al. (1996) Identification of lysine residues required for signal-induced ubiquitination and degradation of I kappa B-alpha in vivo. Oncogene 12, 2425-35
8649784   Curated Info


Baldi L, Brown K, Franzoso G, Siebenlist U (1996) Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha. J Biol Chem 271, 376-9
8550590   Curated Info


Scherer DC, et al. (1995) Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination. Proc Natl Acad Sci U S A 92, 11259-63
7479976   Curated Info