Ser461
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser461  -  ADRB1 (human)

Site Information
GAAADSDssLDEPCR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 89117901

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
norepinephrine ( 1 )

Downstream Regulation
Effects of modification on ADRB1:
intracellular localization ( 1 ) , molecular association, regulation ( 1 ) , receptor internalization, induced ( 1 )
Induce interaction with:
ARRB1 (human) ( 1 )

References 

1

Hinz L, et al. (2017) Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment. PLoS One 12, e0176450
28472170   Curated Info