Tyr231
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Home > Phosphorylation Site Page: > Tyr231  -  DYN1 (rat)

Site Information
LLPLRRGyIGVVNRS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447605

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , immunoprecipitation ( 2 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Src (rat) ( 2 )
Kinases, in vitro:
Src (human) ( 1 )
Treatments:
EGF ( 1 ) , isoproterenol ( 2 )

Downstream Regulation
Effects of modification on DYN1:
activity, inhibited ( 2 ) , molecular association, regulation ( 1 , 2 ) , protein conformation ( 1 ) , receptor internalization, altered ( 2 )

References 

1

Ahn S, et al. (2002) Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor. J Biol Chem 277, 26642-51
12011079   Curated Info

2

Ahn S, et al. (1999) Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling. J Biol Chem 274, 1185-8
9880482   Curated Info