Ser26
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Home > Phosphorylation Site Page: > Ser26  -  PLCB3 (rat)

Site Information
VETLRRGsKFIKWDE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448449

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , VSMC-aorta ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKG2 (rat) ( 1 )
Kinases, in vitro:
PKG2 (rat) ( 1 )
Treatments:
cGMP_analog ( 1 )

Downstream Regulation
Effects of modification on PLCB3:
enzymatic activity, inhibited ( 1 )

References 

1

Xia C, et al. (2001) Phosphorylation and regulation of G-protein-activated phospholipase C-beta 3 by cGMP-dependent protein kinases. J Biol Chem 276, 19770-7
11278298   Curated Info

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