Thr680
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Home > Phosphorylation Site Page: > Thr680  -  BUB1B (human)

Site Information
IEDsREAtHSsGFSG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 484623

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )
Kinases, in vitro:
PLK1 (human) ( 1 )

Downstream Regulation
Effects of modification on BUB1B:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )
Induce interaction with:
PPP2R5A (human) ( 1 )

References 

1

Suijkerbuijk SJ, Vleugel M, Teixeira A, Kops GJ (2012) Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments. Dev Cell 23, 745-55
23079597   Curated Info