Ser26
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Home > Phosphorylation Site Page: > Ser26  -  RHOA (mouse)

Site Information
TCLLIVFsKDQFPEV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 484601

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , liver ( 2 ) , neuron-'brain, cerebral cortex' ( 1 )

Upstream Regulation
Kinases, in vitro:
MST3 (mouse) ( 1 )

Downstream Regulation
Effects of modification on RHOA:
activity, inhibited ( 1 )
Effects of modification on biological processes:
cell motility, inhibited ( 1 ) , cytoskeletal reorganization ( 1 )

References 

1

Tang J, et al. (2014) Cdk5-Dependent Mst3 Phosphorylation and Activity Regulate Neuronal Migration through RhoA Inhibition. J Neurosci 34, 7425-36
24872548   Curated Info

2

Dai J, et al. (2007) Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry. J Proteome Res 6, 250-62
17203969   Curated Info