Ser101
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Home > Phosphorylation Site Page: > Ser101  -  RhoGDI alpha (rat)

Site Information
LESFKkQsFVLkEGV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 452195

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:
PC-12 (chromaffin) ( 1 )

Upstream Regulation
Putative in vivo kinases:
PAK2 (human) ( 1 )
Kinases, in vitro:
PAK2 (human) ( 1 )

Downstream Regulation
Effects of modification on RhoGDI alpha:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 1 )
Inhibit interaction with:
CDC42 iso1 (human) ( 1 ) , RAC1 (rat) ( 1 )

References 

1

Shin EY, et al. (2009) Phosphorylation of RhoGDI1 by p21-activated kinase 2 mediates basic fibroblast growth factor-stimulated neurite outgrowth in PC12 cells. Biochem Biophys Res Commun 379, 384-9
19103160   Curated Info

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