Thr477

Site Information
SPRTLSPtPSAEGYQ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 481465

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Relevant cell line - cell type - tissue:	'fat, brown' ( 3 ) , brain ( 4 ) , heart ( 3 ) , liver ( 1 , 3 ) , liver [leptin (mouse), homozygous knockout] ( 1 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 2 )

References
1	Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83 23140645 Curated Info
2	Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6 21659605 Curated Info
3	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info
4	Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9 20415495 Curated Info