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Site Information |
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ASSsTSVtPDVsDNE SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 449634 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Kinases, in vitro: | |
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Downstream Regulation | |
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Effects of modification on PTEN: | |
Induce interaction with: |
References | |
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Yang JM, et al. (2017) Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization. Oncogene 36, 3673-3685
28263967 Curated Info |
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Carrier M, et al. (2016) Phosphoproteome and Transcriptome of RA-Responsive and RA-Resistant Breast Cancer Cell Lines. PLoS One 11, e0157290
27362937 Curated Info |
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Choi BH, Pagano M, Dai W (2014) Plk1 Protein Phosphorylates Phosphatase and Tensin Homolog (PTEN) and Regulates Its Mitotic Activity during the Cell Cycle. J Biol Chem 289, 14066-74
24706748 Curated Info |
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Bian Y, et al. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics 96, 253-62
24275569 Curated Info |
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Choi BH, Chen Y, Dai W (2013) Chromatin PTEN is involved in DNA damage response partly through regulating Rad52 sumoylation. Cell Cycle 12, 3442-7
24047694 Curated Info |
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Xu D, et al. (2010) Regulation of PTEN stability and activity by Plk3. J Biol Chem 285, 39935-42
20940307 Curated Info |
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Al-Khouri AM, et al. (2005) Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta. J Biol Chem 280, 35195-202
16107342 Curated Info |
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Miller SJ, et al. (2002) Direct identification of PTEN phosphorylation sites. FEBS Lett 528, 145-53
12297295 Curated Info |