Ser25

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Home > Phosphorylation Site Page: > Ser25 - ROMK (mouse)

Site Information
RQRARLVsKDGRCNI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 449605

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	COS (fibroblast) ( 1 ) , oocyte ( 1 )

Upstream Regulation
Putative in vivo kinases:	SGK1 (mouse) ( 1 )
Kinases, in vitro:	PKACA (human) ( 1 ) , SGK1 (mouse) ( 1 )

Downstream Regulation
Effects of modification on ROMK:	activity, induced ( 1 ) , intracellular localization ( 1 )

References
1	Yoo D, et al. (2003) Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A. J Biol Chem 278, 23066-75 12684516 Curated Info

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