Thr163
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Home > Phosphorylation Site Page: > Thr163  -  CASP9 (mouse)

Site Information
PEVLRPEtPRPVDIG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449563

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , phosphoamino acid analysis ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , RAW 264.7 (macrophage) ( 1 ) , retina [DYRK1A (mouse), transfection] ( 2 )

Upstream Regulation
Putative in vivo kinases:
DYRK1A (human) ( 2 )
Kinases, in vitro:
DYRK1A (human) ( 2 ) , DYRK1A (mouse) ( 2 )

Downstream Regulation
Effects of modification on CASP9:
enzymatic activity, inhibited ( 2 )
Effects of modification on biological processes:
apoptosis, altered ( 2 )

References 

1

Pinto SM, et al. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-44
25367039   Curated Info

2

Laguna A, et al. (2008) The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development. Dev Cell 15, 841-53
19081073   Curated Info

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