Ser399
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Home > Phosphorylation Site Page: > Ser399  -  MEN1 iso1 (human)

Site Information
EERPGEQsQGTQSQG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 477697

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
ataxia-telangiectasia ( 1 )
Relevant cell line - cell type - tissue:
GM03189 (lymphoblastoid) ( 1 ) , GM03323 ( 1 ) , GM18326 ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ATM (human) ( 1 )
Treatments:
adriamycin ( 1 ) , DNA-PK_inhibitor_II ( 1 ) , ionizing_radiation ( 1 ) , KU-55933 ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on MEN1 iso1:
phosphorylation ( 1 )

References 

1

Francis J, Lin W, Rozenblatt-Rosen O, Meyerson M (2011) The menin tumor suppressor protein is phosphorylated in response to DNA damage. PLoS One 6, e16119
21264250   Curated Info

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