Ser22

Site Information
LGLGAPGsPREAVAG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 7444695

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 3 , 5 , 6 )
Relevant cell line - cell type - tissue:	A498 (renal) ( 5 ) , HCT116 (intestinal) ( 6 ) , liver ( 3 ) , MDA-MB-435S (breast cell) ( 6 ) , MV4-11 (macrophage) ( 6 )

References
1	Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 27251275 Curated Info
2	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
3	Bian Y, et al. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics 96, 253-62 24275569 Curated Info
4	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
5	Schreiber TB, et al. (2010) An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling. Mol Cell Proteomics 9, 1047-62 20071362 Curated Info
6	Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64 19369195 Curated Info