Ser97
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Home > Phosphorylation Site Page: > Ser97  -  BMAL1 (mouse)

Site Information
RRRDKMNsFIDELAS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7359500

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 2 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CK2A1 (mouse) ( 1 , 2 )
Kinases, in vitro:
CK2A1 (human) ( 2 )
Treatments:
H2O2 ( 1 )

Downstream Regulation
Effects of modification on BMAL1:
intracellular localization ( 2 ) , molecular association, regulation ( 1 ) , protein conformation ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 ) , transcription, altered ( 2 ) , transcription, induced ( 1 )

References 

1

Tamaru T, et al. (2013) ROS Stress Resets Circadian Clocks to Coordinate Pro-Survival Signals. PLoS One 8, e82006
24312621   Curated Info

2

Tamaru T, et al. (2009) CK2alpha phosphorylates BMAL1 to regulate the mammalian clock. Nat Struct Mol Biol 16, 446-8
19330005   Curated Info