Thr1529

Site Information
EIEDAsPtkCPITTk SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 7319932

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 )
Disease tissue studied:	breast cancer ( 2 ) , lung cancer ( 2 ) , non-small cell lung cancer ( 2 )
Relevant cell line - cell type - tissue:	BT-20 (breast cell) ( 2 ) , BT-549 (breast cell) ( 2 ) , Calu 6 (pulmonary) ( 2 ) , Flp-In T-Rex-293 (epithelial) [PRKD1 (human), genetic knockin] ( 3 ) , Flp-In T-Rex-293 (epithelial) ( 3 ) , H2009 (pulmonary) ( 2 ) , H2077 (pulmonary) ( 2 ) , H2887 (pulmonary) ( 2 ) , H322M (pulmonary) ( 2 ) , HCC1937 (breast cell) ( 2 ) , HCC2279 (pulmonary) ( 2 ) , HeLa (cervical) ( 5 ) , HeLa S3 (cervical) [PLK1 (human), knockdown, Tet-inducible PLK1 siRNA] ( 4 ) , HeLa S3 (cervical) ( 4 ) , HOP62 (pulmonary) ( 2 ) , K562 (erythroid) ( 1 ) , MCF-7 (breast cell) ( 2 ) , MDA-MB-231 (breast cell) ( 2 ) , MDA-MB-468 (breast cell) ( 2 ) , NCI-H1395 (pulmonary) ( 2 ) , NCI-H1568 (pulmonary) ( 2 ) , NCI-H1648 (pulmonary) ( 2 ) , NCI-H2030 (pulmonary) ( 2 ) , NCI-H2172 (pulmonary) ( 2 ) , NCI-H322 (pulmonary) ( 2 ) , NCI-H647 (pulmonary) ( 2 )

References
1	Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71 23186163 Curated Info
2	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
3	Franz-Wachtel M, et al. (2012) Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells. Mol Cell Proteomics 11, 160-70 22496350 Curated Info
4	Santamaria A, et al. (2011) The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics 10, M110.004457 20860994 Curated Info
5	Chen RQ, et al. (2009) CDC25B mediates rapamycin-induced oncogenic responses in cancer cells. Cancer Res 69, 2663-8 19276368 Curated Info