Lys538

Site Information
HLkDEkEkLLkEkGE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 7106320

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	breast cancer ( 1 ) , colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:	HCT116 (intestinal) ( 1 ) , HEK293T (epithelial) ( 1 ) , MDA-MB-231 (breast cell) ( 1 ) , MEF (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on NRF2:	molecular association, regulation ( 1 )
Effects of modification on biological processes:	transcription, induced ( 1 )
Induce interaction with:	DNA ( 1 )

References
1	Sun Z, Chin YE, Zhang DD (2009) Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Mol Cell Biol 29, 2658-72 19273602 Curated Info