Ser633
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Home > Phosphorylation Site Page: > Ser633  -  SH3KBP1 (mouse)

Site Information
GQRAssPsLFSTEGK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7105306

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 )
Disease tissue studied:
melanoma skin cancer ( 4 )
Relevant cell line - cell type - tissue:
3T3 (fibroblast) ( 5 ) , brain ( 6 ) , liver ( 2 ) , macrophage-peritoneum [MPRIP (mouse), homozygous knockout] ( 1 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 3 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 4 )

Upstream Regulation
Treatments:
NAG-thiazoline ( 5 ) , okadaic_acid ( 5 ) , PUGNAc ( 5 )

References 

1

Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51
22942356   Curated Info

2

Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645   Curated Info

3

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

4

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info

5

Wang Z, Gucek M, Hart GW (2008) Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A 105, 13793-8
18779572   Curated Info

6

Zhou J (2008) CST Curation Set: 3807; Year: 2008; Biosample/Treatment: tissue, brain/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]P , PTMScan(R) PLK Binding Motif (SpTP) Immunoaffinity Beads Cat#: 1995
Curated Info