Ser33

Site Information
sQLPLsGsRLKRRPD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 7103193
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 )
Disease tissue studied:	breast cancer ( 1 ) , lung cancer ( 3 ) , non-small cell lung cancer ( 3 , 5 ) , non-small cell lung adenocarcinoma ( 3 , 5 )
Relevant cell line - cell type - tissue:	A549 (pulmonary) ( 3 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 2 , 6 , 7 ) , Jurkat (T lymphocyte) ( 4 ) , K562 (erythroid) ( 6 ) , lung ( 3 ) , NCI-H1355 (pulmonary) ( 3 ) , NCI-H1792 (pulmonary) ( 3 ) , NCI-H2228 (pulmonary) ( 5 ) , NCI-H23 (pulmonary) ( 3 ) , NCI-H441 (pulmonary) ( 3 )

References
1	Fan G, et al. (2021) The ATM and ATR kinases regulate centrosome clustering and tumor recurrence by targeting KIFC1 phosphorylation. Nat Commun 12, 20 33397932 Curated Info
2	Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94 25159151 Curated Info
3	Rikova K, Hall B (2013) CST Curation Set: 20736, 21163, 30158, 30159, 30160; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
4	Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7 23749302 Curated Info
5	Rikova K (2013) CST Curation Set: 18502; Year: 2013; Biosample/Treatment: cell line, H2228/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pSQ, p[ST]QG Antibodies Used to Purify Peptides prior to LCMS: Phospho-ATM/ATR Substrate (SQ) (D23H2/D69H5) Rabbit mAb Cat#: 9607 Phospho-(Ser/Thr) ATM/ATR Substrate (S/T*QG) (P-S/T2-100) Rabbit mAb Cat#: 6966 Curated Info
6	Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71 23186163 Curated Info
7	Yu LR, et al. (2007) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra. J Proteome Res 6, 4150-62 17924679 Curated Info