Ser1242

Site Information
EKTLPsGsPRPGQLE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 182088304
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 6 , 7 )
Disease tissue studied:	HER2 positive breast cancer ( 1 ) , luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 ) , breast cancer, surrounding tissue ( 1 ) , breast cancer, triple negative ( 1 ) , lung cancer ( 3 , 4 ) , non-small cell lung cancer ( 3 , 4 ) , non-small cell lung adenocarcinoma ( 3 , 4 ) , non-small cell large cell lung carcinoma ( 3 )
Relevant cell line - cell type - tissue:	breast ( 1 ) , DMS153 (pulmonary) ( 4 ) , HCC78 (pulmonary) ( 3 ) , HeLa (cervical) ( 2 ) , K562 (erythroid) ( 6 ) , lung ( 3 , 4 ) , NCI-H1437 (pulmonary) ( 4 ) , NCI-H1781 (pulmonary) ( 3 ) , NCI-H2073 (pulmonary) ( 4 ) , NCI-H209 (pulmonary) ( 4 ) , NCI-H2228 (pulmonary) ( 3 ) , NCI-H3122 (pulmonary) ( 3 ) , NCI-H3255 (pulmonary) ( 7 ) , NCI-H661 (pulmonary) ( 3 ) , NCI-H838 (pulmonary) ( 4 )

References
1	Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 27251275 Curated Info
2	Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94 25159151 Curated Info
3	Rikova K, Hall B (2013) CST Curation Set: 20740, 21167, 30170, 30171, 30172; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
4	Rikova K, Hall B (2013) CST Curation Set: 20742, 21169, 30176, 30177, 30178; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
5	Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21 23312004 Curated Info
6	Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71 23186163 Curated Info
7	Possemato A (2009) CST Curation Set: 7305; Year: 2009; Biosample/Treatment: cell line, NCI-H3255/-; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info