Ser1023

Site Information
AMBIGUOUS SITES: ognl.NoConversionPossible:
SSNHCsPsGsPHRVD SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 7102085

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	melanoma skin cancer ( 3 )
Relevant cell line - cell type - tissue:	32Dcl3 (myeloid) [FLT3 (mouse), transfection, chimera with human FLT3-ITD mutant (corresponding to wild type P36888 ( 2 ) , 32Dcl3 (myeloid) ( 2 ) , macrophage-bone marrow ( 1 ) , macrophage-bone marrow [DUSP1 (mouse), homozygous knockout] ( 1 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 3 )

References
1	Weintz G, et al. (2010) The phosphoproteome of toll-like receptor-activated macrophages. Mol Syst Biol 6, 371 20531401 Curated Info
2	Choudhary C, et al. (2009) Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes. Mol Cell 36, 326-39 19854140 Curated Info
3	Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26 19367708 Curated Info