Thr119
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Home > Phosphorylation Site Page: > Thr119  -  eIF3-epsilon (human)

Site Information
GAARVIGtLLGTVDK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 7098400

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , phosphoamino acid analysis ( 1 ) , western blotting ( 1 )
Disease tissue studied:
melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK19 (human) ( 1 )
Kinases, in vitro:
CDK19 (human) ( 1 )

Downstream Regulation
Effects of modification on eIF3-epsilon:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , translation, altered ( 1 )
Induce interaction with:
eIF3-eta (human) ( 1 )

References 

1

Shi J, Hershey JW, Nelson MA (2009) Phosphorylation of the eukaryotic initiation factor 3f by cyclin-dependent kinase 11 during apoptosis. FEBS Lett 583, 971-7
19245811   Curated Info