Ser257
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Home > Phosphorylation Site Page: > Ser257  -  Ets-1 (human)

Site Information
DsFEsIEsyDsCDRL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449319

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CAMK2A (human) ( 2 )
Kinases, in vitro:
CAMK2A (human) ( 2 )

Downstream Regulation
Effects of modification on Ets-1:
activity, inhibited ( 2 ) , molecular association, regulation ( 2 )
Effects of modification on biological processes:
transcription, inhibited ( 2 )
Inhibit interaction with:
DNA ( 2 )

References 

1

Guo A (2012) CST Curation Set: 13866; Year: 2012; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) PKD Substrate Antibody Cat#: 4381, PTMScan(R) Phospho-PKD Substrate Motif (LXRXXpS/pT) Immunoaffinity Beads Cat#: 1986
Curated Info

2

Liu H, Grundström T (2002) Calcium regulation of GM-CSF by calmodulin-dependent kinase II phosphorylation of Ets1. Mol Biol Cell 13, 4497-507
12475968   Curated Info