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Site Information |
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MCRLDIDsAPItARN SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 476070 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
Putative in vivo kinases: | |
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Downstream Regulation | |
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Effects of modification on PKM: | |
Effects of modification on biological processes: |
References | |
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Li X, et al. (2023) Pantothenate Kinase 4 Governs Lens Epithelial Fibrosis by Negatively Regulating Pyruvate Kinase M2-Related Glycolysis. Aging Dis 14, 1834-1852
37196116 Curated Info |
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Zhao Z, et al. (2023) The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis. Proc Natl Acad Sci U S A 120, e2212613120
37126714 Curated Info |
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Lorenzana-Carrillo MA, et al. (2022) TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure. Sci Transl Med 14, eabm3565
36322626 Curated Info |
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Alquraishi M, et al. (2022) Podocyte specific deletion of PKM2 ameliorates LPS-induced podocyte injury through beta-catenin. Cell Commun Signal 20, 76
35637461 Curated Info |
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Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079 Curated Info |
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Wiśniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495 Curated Info |