Thr405

Site Information
EGDDtEEtEDyRQFR SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 476574

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:	lung cancer ( 2 ) , non-small cell lung cancer ( 2 ) , melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:	Calu 6 (pulmonary) ( 2 ) , H2009 (pulmonary) ( 2 ) , H2887 (pulmonary) ( 2 ) , HCC1359 (pulmonary) ( 2 ) , HCC2279 (pulmonary) ( 2 ) , HCC366 (pulmonary) ( 2 ) , HCC4006 (pulmonary) ( 2 ) , HCC78 (pulmonary) ( 2 ) , HCC827 (pulmonary) ( 2 ) , HEK293T (epithelial) ( 4 ) , HUES-9 ('stem, embryonic') ( 3 ) , LCLC-103H (pulmonary) ( 2 ) , NCI-H1395 (pulmonary) ( 2 ) , NCI-H1648 (pulmonary) ( 2 ) , NCI-H2030 (pulmonary) ( 2 ) , NCI-H2172 (pulmonary) ( 2 ) , WM239A (melanocyte) ( 1 )

References
1	Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. Mol Cell Proteomics 14, 1599-615 25850435 Curated Info
2	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
3	Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3 21406692 Curated Info
4	Molina H, et al. (2007) Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry. Proc Natl Acad Sci U S A 104, 2199-204 17287340 Curated Info