Ser411
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Home > Phosphorylation Site Page: > Ser411  -  PPP3CA (rat)

Site Information
GKMARVFsVLREESE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2048309

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'heart, ventricle' ( 1 ) , myocyte-heart ( 1 )

Upstream Regulation
Putative in vivo kinases:
CAMK2A (human) ( 1 )
Kinases, in vitro:
CAMK2D (human) ( 1 )

Downstream Regulation
Effects of modification on PPP3CA:
intracellular localization ( 1 ) , phosphorylation ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , signaling pathway regulation ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
cardiomyopathy ( 1 )

References 

1

MacDonnell SM, et al. (2009) CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes. Circ Res 105, 316-25
19608982   Curated Info

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