Tyr139
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Home > Phosphorylation Site Page: > Tyr139  -  Calmodulin (rat)

Site Information
DGDGQVNyEEFVQMM   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448708

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phosphopeptide mapping ( 3 )
Relevant cell line - cell type - tissue:
CHO (fibroblast) [EphB1 (human), transfection] ( 3 ) , E.coli (bacterial) ( 1 )

Upstream Regulation
Kinases, in vitro:
EGFR (human) ( 2 ) , INSR (human) ( 3 ) , Src (human) ( 1 , 2 )
Treatments:
insulin ( 3 )

Downstream Regulation
Effects of modification on Calmodulin:
activity, induced ( 1 ) , protein stabilization ( 1 )

References 

1

Stateva SR, et al. (2015) Characterization of phospho-(tyrosine)-mimetic calmodulin mutants. PLoS One 10, e0120798
25830911   Curated Info

2

Salas V, et al. (2005) Characterisation of tyrosine-phosphorylation-defective calmodulin mutants. Protein Expr Purif 41, 384-92
15866726   Curated Info

3

Joyal JL, Crimmins DL, Thoma RS, Sacks DB (1996) Identification of insulin-stimulated phosphorylation sites on calmodulin. Biochemistry 35, 6267-75
8639568   Curated Info