Lys50
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Home > Acetylation Site Page: > Lys50  -  14-3-3 gamma (mouse)

Site Information
NLLsVAykNVVGARR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 474722

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) [HDAC6 (mouse), heterozygous knockout] ( 2 )

Upstream Regulation
Treatments:
cAMP_analog ( 1 )

Downstream Regulation
Effects of modification on 14-3-3 gamma:
molecular association, regulation ( 1 )
Induce interaction with:
14-3-3 gamma (mouse) ( 1 ) , STAR (mouse) ( 1 )

References 

1

Aghazadeh Y, Ye X, Blonder J, Papadopoulos V (2014) Protein modifications regulate the role of 14-3-3γ adaptor protein in cAMP-induced steroidogenesis in MA-10 Leydig cells. J Biol Chem 289, 26542-53
25086053   Curated Info

2

Li Y (2006) CST Curation Set: 1907; Year: 2006; Biosample/Treatment: cell line, MEF[HDAC6(heterozygous knockout)]/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Antibodies Used to Purify Peptides prior to LCMS: Acetylated-Lysine (Ac-K2-100) Rabbit mAb Cat#: 9814, PTMScan(R) Acetyl-Lys Motif (Ac-K) Immunoaffinity Beads Cat#: 1989
Curated Info