Thr406
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Home > Phosphorylation Site Page: > Thr406  -  MYO6 (pig)

Site Information
TAGGAKGtVIKVPLK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 449089

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:
Caco-2 (intestinal) ( 1 )

Upstream Regulation
Kinases, in vitro:
PAK3 (human) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Naccache SN, Hasson T (2006) Myosin VI altered at threonine 406 stabilizes actin filaments in vivo. Cell Motil Cytoskeleton 63, 633-45
16917816   Curated Info

2

Morris CA, et al. (2003) Calcium functionally uncouples the heads of myosin VI. J Biol Chem 278, 23324-30
12682054   Curated Info