Ser359
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Home > Phosphorylation Site Page: > Ser359  -  PKCD (human)

Site Information
HKVLGkGsFGkVLLG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 6319238

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 3 ) , mutation of modification site ( 1 , 2 ) , phospho-antibody ( 1 , 2 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 , 2 ) , Jurkat (T lymphocyte) ( 3 ) , myocyte-heart ( 1 )

Upstream Regulation
Treatments:
H2O2 ( 2 )

Downstream Regulation
Effects of modification on PKCD:
enzymatic activity, altered ( 2 )

References 

1

Gong J, Park M, Steinberg SF (2017) CLEAVAGE ALTERS THE MOLECULAR DETERMINANTS OF PROTEIN KINASE C-δ CATALYTIC ACTIVITY. Mol Cell Biol
28784722   Curated Info

2

Gong J, et al. (2015) The C2 Domain and Altered ATP-Binding Loop Phosphorylation at Ser³⁵⁹ Mediate the Redox-Dependent Increase in Protein Kinase C-δ Activity. Mol Cell Biol 35, 1727-40
25755284   Curated Info

3

Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302   Curated Info